Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TSC22D3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TSC22D3 |
| Key Genes/Proteins | NPY1R, NFKBIA, SESN1, PDK4, AUTOPHAGY, MYH2 |
| Related Pathways | Autophagy, Mtor, Immune Response |
Knowledge base pages for this entity
graph TD
TSC22D3["TSC22D3"]
TSC22D3 -->|"encodes"| GILZ["GILZ"]
TSC22D3 -->|"regulates"| NPY1R["NPY1R"]
TSC22D3 -->|"regulates"| Autophagy["Autophagy"]
TSC22D3 -->|"regulates"| Mtor["Mtor"]
TSC22D3 -->|"regulates"| Immune_Response["Immune Response"]
TSC22D3 -->|"regulates"| NFKBIA["NFKBIA"]
TSC22D3 -->|"regulates"| SESN1["SESN1"]
TSC22D3 -->|"regulates"| PDK4["PDK4"]
PPP5C["PPP5C"] -->|"regulates"| TSC22D3
JUN["JUN"] -->|"regulates"| TSC22D3
ADRA1D["ADRA1D"] -->|"regulates"| TSC22D3
PDK4 -->|"regulates"| TSC22D3
LITAF["LITAF"] -->|"regulates"| TSC22D3
IL6R["IL6R"] -->|"regulates"| TSC22D3
CCND1["CCND1"] -->|"regulates"| TSC22D3
MERTK["MERTK"] -->|"regulates"| TSC22D3| Target | Relation | Type | Str |
|---|---|---|---|
| NPY1R | regulates | gene | 0.60 |
| Autophagy | regulates | pathway | 0.60 |
| Mtor | regulates | pathway | 0.60 |
| Immune Response | regulates | pathway | 0.60 |
| NFKBIA | regulates | gene | 0.60 |
| SESN1 | regulates | gene | 0.60 |
| PDK4 | regulates | gene | 0.60 |
| AUTOPHAGY | regulates | gene | 0.60 |
| MYH2 | regulates | gene | 0.60 |
| CDKN1A | regulates | gene | 0.60 |
| JUN | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| NDRG2 | regulates | gene | 0.60 |
| CALM2 | regulates | gene | 0.60 |
| MTORC1 | regulates | gene | 0.60 |
| CCND1 | regulates | gene | 0.60 |
| GENES | regulates | gene | 0.60 |
| SOX2 | regulates | gene | 0.60 |
| HDC | regulates | gene | 0.60 |
| SOX9 | regulates | gene | 0.60 |
| MERTK | regulates | gene | 0.60 |
| IRF1 | regulates | gene | 0.60 |
| Cell Cycle | regulates | pathway | 0.60 |
| ADRA1D | regulates | gene | 0.60 |
| ADCY9 | regulates | gene | 0.60 |
| VPS37B | regulates | gene | 0.60 |
| Actin | regulates | protein | 0.60 |
| DUSP1 | regulates | gene | 0.60 |
| PPP5C | regulates | gene | 0.60 |
| LITAF | regulates | gene | 0.60 |
| Nfkb | regulates | protein | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PPP5C | regulates | gene | 0.60 |
| JUN | regulates | gene | 0.60 |
| ADRA1D | regulates | gene | 0.60 |
| PDK4 | regulates | gene | 0.60 |
| LITAF | regulates | gene | 0.60 |
| IL6R | regulates | gene | 0.60 |
| CCND1 | regulates | gene | 0.60 |
| MERTK | regulates | gene | 0.60 |
| DUSP1 | regulates | gene | 0.60 |
| ADCY9 | regulates | gene | 0.60 |
| AUTOPHAGY | regulates | gene | 0.60 |
| SOX2 | regulates | gene | 0.60 |
| CDKN1A | regulates | gene | 0.60 |
| SESN1 | regulates | gene | 0.60 |
| IRF1 | regulates | gene | 0.60 |
| NDRG2 | regulates | gene | 0.60 |
| SOX9 | regulates | gene | 0.60 |
| MYH2 | regulates | gene | 0.60 |
| VPS37B | regulates | gene | 0.60 |
| MTORC1 | regulates | gene | 0.60 |
| NFKBIA | regulates | gene | 0.60 |
| CALM2 | regulates | gene | 0.60 |
| NPY1R | regulates | gene | 0.60 |
| HDC | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||