PDK4

Understanding Entity Pages

This page aggregates everything SciDEX knows about PDK4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PDK4 is a gene implicated in neurodegeneration research. Key relationships include: associated with, inhibits, expressed in. Associated with Als, Cancer, Carcinoma. Connected to 34 entities in the SciDEX knowledge graph.

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graph TD
    PDK4["<b>PDK4</b>"]
    Cardiovascular{"Cardiovascular"}
    PDK4 -->|"inhibits"| Cardiovascular
    Als{"Als"}
    PDK4 -->|"inhibits"| Als
    Tumor{"Tumor"}
    PDK4 -->|"inhibits"| Tumor
    Hypertension{"Hypertension"}
    PDK4 -->|"inhibits"| Hypertension
    Ms{"Ms"}
    PDK4 -->|"associated with"| Ms
    Diabetes{"Diabetes"}
    PDK4 -->|"expressed in"| Diabetes
    PDK4 -->|"expressed in"| Ms
    PDK4 -->|"expressed in"| Cardiovascular
    SOD1["SOD1"]
    PDK4 -->|"associated with"| SOD1
    TNFR2["TNFR2"]
    PDK4 -->|"associated with"| TNFR2
    BCL2["BCL2"]
    PDK4 -->|"associated with"| BCL2
    SLC16A1["SLC16A1"]
    PDK4 -->|"associated with"| SLC16A1
    SOD2["SOD2"]
    SOD2 -->|"associated with"| PDK4
    CAT["CAT"]
    CAT -->|"associated with"| PDK4
    BAX["BAX"]
    BAX -->|"associated with"| PDK4
    SPR["SPR"]
    SPR -->|"associated with"| PDK4
    PPARGC1A["PPARGC1A"]
    PPARGC1A -->|"associated with"| PDK4
    CASP3["CASP3"]
    CASP3 -->|"associated with"| PDK4
    PDK1["PDK1"]
    PDK1 -->|"associated with"| PDK4
    BCL2L1["BCL2L1"]
    BCL2L1 -->|"expressed in"| PDK4
    IGF1R["IGF1R"]
    IGF1R -->|"expressed in"| PDK4
    SERPINE1["SERPINE1"]
    SERPINE1 -->|"expressed in"| PDK4
    style PDK4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0