MERTK

Understanding Entity Pages

This page aggregates everything SciDEX knows about MERTK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MER Proto-Oncogene, Tyrosine Kinase: receptor tyrosine kinase in TAM family involved in microglial phagocytosis and neurodegeneration

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graph TD
    MERTK["<b>MERTK</b>"]
    Neuroinflammation{"Neuroinflammation"}
    MERTK -->|"expressed in"| Neuroinflammation
    Ms{"Ms"}
    MERTK -->|"expressed in"| Ms
    Inflammation{"Inflammation"}
    MERTK -->|"regulates"| Inflammation
    Lymphoma{"Lymphoma"}
    MERTK -->|"activates"| Lymphoma
    MERTK -->|"activates"| Ms
    Atherosclerosis{"Atherosclerosis"}
    MERTK -->|"activates"| Atherosclerosis
    ERK["ERK"]
    MERTK -->|"expressed in"| ERK
    AKT["AKT"]
    MERTK -->|"activates"| AKT
    APOPTOSIS["APOPTOSIS"]
    MERTK -->|"activates"| APOPTOSIS
    MAF["MAF"]
    MERTK -->|"activates"| MAF
    Akt(["Akt"])
    MERTK -->|"activates"| Akt
    Apoptosis(["Apoptosis"])
    MERTK -->|"activates"| Apoptosis
    STAT6["STAT6"]
    STAT6 -->|"expressed in"| MERTK
    EPHA4["EPHA4"]
    EPHA4 -->|"expressed in"| MERTK
    MTOR["MTOR"]
    MTOR -->|"activates"| MERTK
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"expressed in"| MERTK
    ERK -->|"expressed in"| MERTK
    style MERTK fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0