concept

MAST CELLS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAST CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

45Connections

0Hypotheses

0Analyses

11Outgoing

18Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	MAST CELLS
Summary	Page for Mast Cells
Key Genes/Proteins	IL-33
Related Diseases	ALZHEIMER'S DISEASE, STROKE, PULMONARY FIBROSIS

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    MAST_CELLS["MAST CELLS"]
    MAST_CELLS -->|"activates"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
    MAST_CELLS -->|"regulates"| STROKE["STROKE"]
    MAST_CELLS -->|"activates"| NEURON["NEURON"]
    MAST_CELLS -->|"activates"| T_CELLS["T CELLS"]
    MAST_CELLS -->|"implicated in"| NEURODEGENERATION["NEURODEGENERATION"]
    MAST_CELLS -->|"regulates"| MICROGLIA["MICROGLIA"]
    INFLAMMATION["INFLAMMATION"] -->|"regulates"| MAST_CELLS
    IL_33["IL-33"] -->|"activates"| MAST_CELLS
    CYTOKINES["CYTOKINES"] -->|"causes"| MAST_CELLS
    BLOOD_BRAIN_BARRIER["BLOOD-BRAIN BARRIER"] -->|"causes"| MAST_CELLS
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"] -->|"activates"| MAST_CELLS

Outgoing (12)

Target	Relation	Type	Str
NEUROINFLAMMATION	activates	process	0.65
STROKE	regulates	disease	0.35
STROKE	activates	disease	0.35
NEURON	activates	cell_type	0.35
T CELLS	activates	cell_type	0.35
NEUROINFLAMMATION	associated_with	process	0.35
NEURODEGENERATION	implicated_in	process	0.35
NEUROINFLAMMATION	implicated_in	process	0.35
MICROGLIA	regulates	cell_type	0.35
PULMONARY FIBROSIS	interacts_with	disease	0.35
NEUTROPHILS	implicated_in	cell_type	0.35

Incoming (33)

Source	Relation	Type	Str
ALZHEIMER'S DISEASE	associated_with	disease	0.50
INFLAMMATION	regulates	process	0.35
IL-33	activates	gene	0.35
INFLAMMATION	activates	process	0.35
INFLAMMATION	causes	process	0.35
CYTOKINES	causes	protein	0.35
ALPHA-SYNUCLEIN	activates	gene	0.35
CYTOKINES	activates	protein	0.35
AMYLOID	activates	protein	0.35
ALZHEIMER'S DISEASE	activates	disease	0.35
AMYLOID	interacts_with	protein	0.35
HYPOTHALAMUS	activates	brain_region	0.35
MACROPHAGES	interacts_with	cell_type	0.35
FIBROBLASTS	interacts_with	cell_type	0.35
AUTOPHAGY	interacts_with	process	0.35
APOPTOSIS	interacts_with	process	0.35
MACROPHAGES	implicated_in	cell_type	0.35
FIBROBLASTS	implicated_in	cell_type	0.35

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

MAST CELLS

Understanding Entity Pages

Wiki Pages (21)

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Phase 3 Study to Compare the Efficacy and Safety of Masitini... (NCT03127267)

slc17a9

SLC30A5 — Solute Carrier Family 3 Member 0A5 (SLC30A5)

IL25 (Interleukin 25)

Peripheral Immune System in Parkinson's Disease

Triggering Receptor Expressed on Myeloid Cells 3 (TREM3)