Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEUROPATHIC PAIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEUROPATHIC PAIN |
Knowledge base pages for this entity
graph TD
NEUROPATHIC_PAIN["NEUROPATHIC PAIN"]
Immune_System["Immune System"] -->|"involved_in"| NEUROPATHIC_PAIN
ST3GAL2_GT1b_TLR2_Axis["ST3GAL2-GT1b-TLR2 Axis"] -->|"involved_in"| NEUROPATHIC_PAIN
NMDAR2B["NMDAR2B"] -->|"causes"| NEUROPATHIC_PAIN
Microglia_Activation["Microglia Activation"] -->|"causes"| NEUROPATHIC_PAIN
Hcn1_Inhibitors["Hcn1 Inhibitors"] -->|"treats"| NEUROPATHIC_PAIN
FST["FST"] -->|"promotes"| NEUROPATHIC_PAIN
Neuroprotectin_D1["Neuroprotectin D1"] -->|"treats"| NEUROPATHIC_PAIN
IGF1R["IGF1R"] -->|"target for"| NEUROPATHIC_PAIN| Target | Relation | Type | Str |
|---|---|---|---|
| Systemic Inflammation | causes | process | 0.95 |
| systemic inflammation | associated_with | process | 0.90 |
| spinal cord | affects | brain_region | 0.70 |
| macrophages | affects | cell_type | 0.70 |
| microglia | affects | cell_type | 0.70 |
| neurons | affects | cell_type | 0.70 |
| ferroptosis | involves | pathway | 0.60 |
| nicotinic receptor | involves | receptor | 0.60 |
| cortex | affects | brain_region | 0.60 |
| necroptosis | involves | pathway | 0.60 |
| pyroptosis | involves | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| HCN1 | therapeutic_target | entity | 0.85 |
| HCN CHANNELS | associated_with | entity | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||