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gene 1,171 words KG: CHAT
Contents

CHAT Gene

🧬 Gene Info
Gene SymbolCHAT
Chromosome10q11.23
FunctionThe reaction mechanism involves
Subcellular Localizationthe cytoplasm of presynaptic nerve terminals, but also associates with synaptic vesicles for regulated neurotransmitter
Molecular Weight70 kDa
Amino Acids748 aa
Exons14
PathwaysApoptosis, Cell Cycle
GeneCardsCHAT
Human Protein AtlasCHAT
Associated DiseasesAls, Alzheimer, Alzheimer's disease, Anxiety, Dementia
InteractionsABCB1, ACHE, AD, AKT, ALZHEIMER, ALZHEIMER'S DISEASE
SciDEX HypothesesSensory-Motor Circuit Cross-Modal Compensation
Vagal Nerve Stimulation Combined with Probiotic Th
KG Connections390 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (26)

Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62Restoring Neuroprotective Tryptophan Metabolism via Targeted
Score: 0.61Netrin-1 Gradient Restoration
Score: 0.59
← Prevpg 2/2

Related Analyses (15)

Do β-amyloid plaques and neurofibrillary tangles cause or re
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · completedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (2)

Electroacupuncture ST37 treatment for DSS-induced colitis in
validation · proposed · Score: 0.95Creation and validation of 3xAD-ChAT-Cre mouse model
validation · proposed · Score: 0.90

See Also (7)

acetylcholine
general · KG edge: co_discussedABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_withABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: associated_withACE Gene
gene · KG edge: therapeutic_targetADRA2A Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAOB associated_with CHAT
GABRA1 associated_with CHAT
CHAT associated_with CYP2D6
CHAT associated_with APOE
CHAT associated_with HMGCR
CHAT associated_with OPRM1
CHAT associated_with SLC30A8
CHAT associated_with COMT
CHAT associated_with NBEA
CHAT associated_with HTR2C

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