gene 716 words KG: MLST8 2026-03-24
kind:genesection:genesstate:published
Contents

MLST8 Gene

🧬 Gene Info
Gene SymbolMLST8
Full NameMLST8
AliasesGBL, LST8, mLST8 [@maiese2020]
Chromosome16p13.3 [@ehninger2014]
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight36 kDa
Amino Acids326 aa
Exons14
PathwaysMTOR, mtor, mTOR, mTOR signaling, mTOR pathway
UniProt IDQ9BVC4
NCBI Gene ID84923
Ensembl IDENSG00000167985
GeneCardsMLST8
Human Protein AtlasMLST8
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsRICTOR, MTOR, PIK3C3, EGFR, PPARG, HSPA5
KG Connections315 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Packard Center for ALS Research
institution · KG edge: interacts_with
casp3
gene · KG edge: interacts_with
CALCOCO2 — Calcium Binding and Coiled-Coil Domain 2
gene · KG edge: interacts_with
BECN1 Gene
gene · KG edge: interacts_with
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

MLST8 interacts_with RICTOR
MLST8 interacts_with MTOR
MLST8 interacts_with PIK3C3
MLST8 interacts_with EGFR
MLST8 interacts_with PPARG
MLST8 interacts_with HSPA5
MLST8 interacts_with MAVS
MLST8 interacts_with FIP200
MLST8 interacts_with AMBRA1
MLST8 interacts_with APC