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mechanism 1,214 words KG: Er Stress
Contents

ER Stress and Unfolded Protein Response in Neurodegeneration

⚙ Mechanism Info
NameEr Stress
Key Genes/ProteinsABCB1, Actin, ADSL, AGING, AIM2, AKT
Related DiseasesAging, Als, Alzheimer
Related PathwaysAkt

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Related Hypotheses (156)

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Score: 0.73Astrocyte-Mediated Neuronal Epigenetic Rescue
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Score: 0.72Circadian Rhythm Entrainment of Reactive Astrocytes
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Score: 0.72
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Related Analyses (30)

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Related Experiments (30)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Proposed experiment from debate on Astrocytes adopt A1 (neur
falsification · proposed · Score: 0.40s:** - Biochemical binding assays measuring PROTAC selectivi
falsification · proposed · Score: 0.40Proposed experiment from debate on Epigenetic clocks and bio
falsification · proposed · Score: 0.40Proposed experiment from debate on Microglia activate astroc
falsification · proposed · Score: 0.40

See Also (15)

Beta-Propeller Protein-Associated Neurodegeneration (BP
disease · Pages share 139 hypothesesChina Neurodegeneration Epidemiology
disease · Pages share 139 hypothesesNeuroimaging for Parkinsonian Syndromes (NCT03872102)
clinical · Pages share 27 hypothesesSynaptic Biomarkers in Neurodegeneration
biomarker · Pages share 139 hypothesesOlfactory Mucosa, Blood and Urine for Identification of
clinical · Pages share 139 hypotheses

Knowledge Graph (12 edges)

CERS2 associated_with Er Stress
HSPA1A activates Er Stress
ERK1 activates Er Stress
JUN regulates Er Stress
G3BP1 regulates Er Stress
VALOSIN regulates Er Stress
VCP regulates Er Stress
CXCL2 inhibits Er Stress
IL6 inhibits Er Stress
ATF4 activates Er Stress

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