| Gene Symbol | ERK1 |
| Chromosome | 16p11.2 |
| Protein Type | Kinase |
| Function | is a serine/threonine protein kinase that plays a central role in intracellular signal transduction. |
| Primary Expression | various tissues, with particularly high levels in the brain where it participates in learning, memory, and neuronal plasticity |
| Subcellular Localization | </th><td>Cytoplasm, nucleus</td></tr> [@roskoski2012] |
| Molecular Weight | 44 kDa |
| Amino Acids | 402 aa |
| Pathways | Akt, Apoptosis, Differentiation, G-Protein Coupled Receptor, Hedgehog |
| Ensembl ID | ENSG00000102882 |
| GeneCards | ERK1 |
| Human Protein Atlas | ERK1 |
| Associated Diseases | AD, ALI, AMI, Aging, Als, Alzheimer |
| Known Drugs/Compounds | curcumin, rapamycin, metformin |
| Interactions | FGF2, NRF2, KEAP1, AKT, GNAQ, STX17 |
| KG Connections | 943 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |