| Gene Symbol | FUS |
| Full Name | FUS (Fused in Sarcoma) |
| Chromosome | 16p11.2. |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Pathways | Blood-Brain Barrier, Hippo Pathway, Oxidative Stress, Sod1, Tdp-43 |
| UniProt ID | Search UniProt |
| GeneCards | FUS |
| Human Protein Atlas | FUS |
| RGG1 domain (residues 165–267) | The first arginine-glycine-glycine repeat region, which contributes to RNA binding and phase separation through electrostatic interactions. |
| RGG2 domain (residues 370–422) | The second RGG repeat region. |
| RGG3 domain (residues 453–501) | The third RGG repeat region. |
| Associated Diseases | AD, Aging, ALI, als |
| Known Drugs/Compounds | ADUCANUMAB, Antisense Oligonucleotide, Rna Oligonucleotides, RNA oligonucleotides |
| Interactions | ACTB, Actin, AD, AGING, ALPHA-SYNUCLEIN, ALS |
| SciDEX Hypotheses | ASO-Mediated Exon Skipping to Restore FUS-TAZ Chap FUS Phase Separation Dominance in FTD-TDP: Aberran Arginine Methylation Loss on FUS RGG Domains Drive (+6 more) |
| KG Connections | 1564 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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