protein 2,292 words KG: LAMP2A
Contents

LAMP2A Protein — Lysosomal-Associated Membrane Protein 2A

🔬 Protein Info
Gene SymbolLAMP2A
Full Namelamp2a
Protein TypeProtein
Molecular Weight45 kDa
Amino Acids12 aa
Exons9
PathwaysAutophagy, Chaperone, Oxidative Stress, Proteostasis
UniProt IDSearch UniProt
GeneCardsLAMP2A
Human Protein AtlasLAMP2A
Associated DiseasesALS, Aging, Alzheimer, Amyotrophic Lateral Sclerosis, Ataxia
Known Drugs/Compoundsrapamycin
InteractionsATG10, CALCINEURIN, ATG12, LAMP1, LAMP2, BCL2
KG Connections438 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (14)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.61
Autophagosome Maturation Checkpoint Control
Score: 0.49
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48

Related Analyses (8)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

Related Experiments (4)

Alpha-Synuclein Spreading Mechanism — Prion-Like Propagation
exploratory · proposed · Score: 0.40
Chaperone-Mediated Autophagy Dysfunction in PD - Experiment
clinical · proposed · Score: 0.40
Gene expression analysis of autophagy targets following treh
exploratory · proposed · Score: 0.85
Trehalose-induced autophagy gene expression analysis
exploratory · proposed · Score: 0.85

See Also (8)

Packard Center for ALS Research
institution · KG edge: activates
ATG12 — Autophagy Related 12
gene · KG edge: activates
ATG10 Gene
gene · KG edge: activates
ar
gene · KG edge: activates
ACTB Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

LAMP2A activates ATG10
LAMP2A associated_with LAMP1
LAMP2A associated_with KAT2A
LAMP2A associated_with TP53
LAMP2A associated_with FIP200
LAMP2A associated_with RUBCN
LAMP2A associated_with LGALS3
LAMP2A associated_with PPARGC1A
LAMP2A associated_with STUB1
LAMP2A activates CALCINEURIN