| Gene Symbol | MAPK1 |
| Chromosome | 22q11.2 |
| Protein Family | MAP kinase family, CMGC group |
| Protein Type | Kinase |
| Function | is a protein involved in various cellular processes relevant to neurodegeneration. |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | 41 kDa |
| Amino Acids | 360 aa |
| Pathways | MAPK, Mapk, MAPK signaling, MAPK pathway |
| UniProt ID | P28482 |
| GeneCards | MAPK1 |
| Human Protein Atlas | MAPK1 |
| MAPK3 (ERK1) | Paralogous kinase with overlapping but distinct functions |
| MEK1/MEK2 | Upstream activating kinases |
| RAF proteins | Further upstream components of the cascade |
| Associated Diseases | ALS, Aging, Alzheimer, Cancer, Carcinoma |
| Known Drugs/Compounds | Zuojin Pill, Chrysotoxine, DEP, DMP, DOP |
| Interactions | MAP1LC3B, MTOR, TLR4, LC3, TFEB, AKT |
| KG Connections | 948 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |