gene

TERC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TERC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

62Connections
0Hypotheses
2Analyses
43Outgoing
19Incoming

Summary

TERC is a gene implicated in neurodegeneration research. Key relationships include: regulates, associated with, contributes to. Associated with ALS, Aging, Als. Connected to 36 entities in the SciDEX knowledge graph.

View on Wiki →

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
RNA TypeLong non-coding RNA (lncRNA)
Length~451 nucleotides
Associated DiseasesALS, Inflammation, Ms, Senescence
InteractionsMICRORNAS, IL-6, IL-8
KG Connections62 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

TERC Gene

gene · 1067 words

TERT Gene

gene · 2962 words

TERT Gene

gene · 2193 words

TERT Protein

protein · 1674 words

Telomere Dysfunction in Neurodegeneration

mechanism · 1567 words

Telomere Dysfunction-Associated Neurons

cell · 1091 words

Pathway Diagram

graph TD
    TERC["<b>TERC</b>"]
    Senescence{"Senescence"}
    TERC -->|"regulates"| Senescence
    Als{"Als"}
    TERC -->|"associated with"| Als
    Ms{"Ms"}
    TERC -->|"regulates"| Ms
    Inflammation{"Inflammation"}
    TERC -->|"regulates"| Inflammation
    TERC -->|"associated with"| Inflammation
    TERC -->|"associated with"| Senescence
    Aging{"Aging"}
    TERC -->|"contributes to"| Aging
    TERC -->|"associated with"| Ms
    Cancer{"Cancer"}
    TERC -->|"contributes to"| Cancer
    TERC -->|"expressed in"| Als
    TERC -->|"expressed in"| Ms
    Schizophrenia{"Schizophrenia"}
    TERC -->|"expressed in"| Schizophrenia
    TERT["TERT"]
    TERT -->|"associated with"| TERC
    AGING["AGING"]
    AGING -->|"contributes to"| TERC
    CANCER["CANCER"]
    CANCER -->|"contributes to"| TERC
    TERT -->|"expressed in"| TERC
    AGING -->|"regulates"| TERC
    CANCER -->|"regulates"| TERC
    P21["P21"]
    P21 -->|"regulates"| TERC
    style TERC fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (43)

TargetRelationTypeStr
Telomere Dysfunctioncausesmechanism0.95
Telomere Dysfunctionregulatesmechanism0.85
Telomere Maintenanceinvolved_inprocess0.85
Telomere Dysfunctioninvolved_inprocess0.80
Senescenceregulatesdisease0.65

Incoming (19)

SourceRelationTypeStr
TERTassociated_withgene0.60
TERTexpressed_ingene0.60
TERTencodesgene0.60
AGINGcontributes_togene0.60
CANCERcontributes_togene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (2)

Scientific analyses that reference this entity

What determines the selectivity and efficiency of intercellular transmission pat

neurodegeneration | 2026-04-08 | 0 hypotheses

Tau propagation mechanisms and therapeutic interception points

neurodegeneration | 2026-04-02 | 0 hypotheses

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found