gene 897 words KG: PPARD
Contents

PPARD Gene

🧬 Gene Info
Gene SymbolPPARD
Full Nameppard
AliasesPPARδ, PPAR-beta, NR1C2
Chromosome6p21.31
Protein TypeGene
FunctionTarget genes are involved in: - Fatty acid oxidation - Glucose metabolism - Lipid metabolism - Inflammation - Cell proliferation and differentiation
PathwaysAkt, Mapk, Sphingolipid
NCBI Gene ID5468
GeneCardsPPARD
Human Protein AtlasPPARD
Associated Diseasesneurodegeneration
Known Drugs/CompoundsKd3010, T3D-959, KD3010, Bezafibrate
InteractionsPPARGC1A
KG Connections151 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (9)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.76
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71

Related Analyses (4)

Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Related Experiments (1)

Proposed experiment from debate on Epigenetic clocks and bio
falsification · proposed · Score: 0.40

See Also (15)

Packard Center for ALS Research
institution · KG edge: therapeutic_target
FGF18 Gene
gene · KG edge: therapeutic_target
EP300 Gene
gene · KG edge: therapeutic_target
DKK1 — Dickkopf WNT Signaling Pathway Inhibitor 1
gene · KG edge: therapeutic_target
CTNNB1 — Catenin Beta 1
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

PPARD therapeutic_target CLDN1
PPARD therapeutic_target APC
PPARD therapeutic_target AXIN1
PPARD therapeutic_target PTGS2
PPARD therapeutic_target CREBBP
PPARD therapeutic_target HMOX1
PPARD therapeutic_target ADRB2
PPARD therapeutic_target ATG5
PPARD therapeutic_target NEUROD1
PPARD therapeutic_target FGF20

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