| Gene Symbol | IL1B |
| Full Name | Interleukin-1 Beta |
| Chromosome | 2q14.1 |
| Protein Type | Ligand |
| Target Class | Ligand |
| Function | IL-1 receptor antagonist or neutralizing monoclonal antibody |
| Mechanism of Action | IL-1 receptor antagonist or neutralizing monoclonal antibody |
| Subcellular Localization | </th><td>Secreted, cytosol</td></tr> |
| Druggability | Medium (0.49) |
| Clinical Stage | Approved |
| Molecular Weight | 31 kDa |
| Amino Acids | 269 aa |
| Exons | 7 |
| Pathways | Akt, Apoptosis, Epigenetic, Mapk, Oxidative Stress |
| UniProt ID | O43645 |
| NCBI Gene ID | 3553 |
| Ensembl ID | ENSG00000125538 |
| OMIM | 164520 |
| GeneCards | IL1B |
| Human Protein Atlas | IL1B |
| Associated Diseases | AD, ALS, AMI, Aging, Alzheimer |
| Known Drugs/Compounds | Berberine, berberine, Guhan Yangsheng Jing, resveratrol, ANTHOCYANINS, rapamycin |
| Interactions | NLRP3, CASP1, PYCARD, SLC7A11, GPX4, TP53 |
| SciDEX Target | View Target Profile (8 clinical trials) |
| KG Connections | 1865 knowledge graph edges |
| Databases | GeneCardsHPASTRING |