Optogenetic Control of Mitochondrial Transfer Networks

**Background and Rationale** Mitochondrial dysfunction represents a central pathological hallmark across the spectrum of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease. Compromised mitochondrial bioenergetics, impaired calcium buffering, and excessive reactive oxygen species production contribute to neuronal vulnerability and progressive cell death. Recent groundbreaking discoveries have revealed that astro...