COFILIN

Understanding Entity Pages

This page aggregates everything SciDEX knows about COFILIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

COFILIN is a protein involved in neurodegeneration research. Key relationships include: inhibits, expressed in, implicated in. Associated with Alzheimer. Connected to 12 entities in the SciDEX knowledge graph.

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graph TD
    COFILIN["<b>COFILIN</b>"]
    Alzheimer{"Alzheimer"}
    COFILIN -->|"inhibits"| Alzheimer
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    COFILIN -->|"inhibits"| ALZHEIMER_S_DISEASE
    PUMA["PUMA"]
    COFILIN -->|"inhibits"| PUMA
    ALZHEIMER["ALZHEIMER"]
    COFILIN -->|"inhibits"| ALZHEIMER
    Neuron["Neuron"]
    COFILIN -->|"expressed in"| Neuron
    Fibroblast["Fibroblast"]
    COFILIN -->|"expressed in"| Fibroblast
    Stem_Cell["Stem Cell"]
    COFILIN -->|"expressed in"| Stem_Cell
    neurodegeneration["neurodegeneration"]
    COFILIN -->|"implicated in"| neurodegeneration
    LIMK1["LIMK1"]
    LIMK1 -->|"inhibits"| COFILIN
    ALZHEIMER_S_DISEASE -->|"inhibits"| COFILIN
    ALZHEIMER -->|"inhibits"| COFILIN
    AND["AND"]
    AND -->|"inhibits"| COFILIN
    PUMA -->|"inhibits"| COFILIN
    style COFILIN fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0