LMX1A

Understanding Entity Pages

This page aggregates everything SciDEX knows about LMX1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    LMX1A["<b>LMX1A</b>"]
    Als["Als"]
    LMX1A -->|"activates"| Als
    Parkinson["Parkinson"]
    LMX1A -->|"inhibits"| Parkinson
    ALS["ALS"]
    LMX1A -->|"activates"| ALS
    NURR1["NURR1"]
    LMX1A -->|"activates"| NURR1
    PRKN["PRKN"]
    LMX1A -->|"activates"| PRKN
    PARKIN["PARKIN"]
    LMX1A -->|"inhibits"| PARKIN
    PARKINSON["PARKINSON"]
    LMX1A -->|"inhibits"| PARKINSON
    Dopaminergic["Dopaminergic"]
    LMX1A -->|"inhibits"| Dopaminergic
    Fibroblast["Fibroblast"]
    LMX1A -->|"activates"| Fibroblast
    Neuron["Neuron"]
    LMX1A -->|"activates"| Neuron
    GENES["GENES"]
    LMX1A -->|"inhibits"| GENES
    ASCL1["ASCL1"]
    LMX1A -->|"activates"| ASCL1
    BDNF["BDNF"]
    LMX1A -->|"activates"| BDNF
    NGF["NGF"]
    LMX1A -->|"activates"| NGF
    UBIQUITIN["UBIQUITIN"]
    LMX1A -->|"inhibits"| UBIQUITIN
    AND["AND"]
    LMX1A -->|"activates"| AND
    GDNF["GDNF"]
    LMX1A -->|"activates"| GDNF
    P53["P53"]
    LMX1A -->|"activates"| P53
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    LMX1A -->|"inhibits"| PARKINSON_S_DISEASE
    NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"]
    LMX1A -->|"inhibits"| NEURODEGENERATIVE_DISORDERS
    NGF["NGF"]
    NGF -->|"activates"| LMX1A
    UBIQUITIN["UBIQUITIN"]
    UBIQUITIN -->|"inhibits"| LMX1A
    ASCL1["ASCL1"]
    ASCL1 -->|"activates"| LMX1A
    GDNF["GDNF"]
    GDNF -->|"activates"| LMX1A
    BDNF["BDNF"]
    BDNF -->|"activates"| LMX1A
    P53["P53"]
    P53 -->|"activates"| LMX1A
    Substantia_Nigra["Substantia Nigra"]
    LMX1A -->|"expressed in"| Substantia_Nigra
    Fibroblast["Fibroblast"]
    LMX1A -->|"expressed in"| Fibroblast
    Neuron["Neuron"]
    LMX1A -->|"expressed in"| Neuron
    neurodegeneration["neurodegeneration"]
    LMX1A -->|"implicated in"| neurodegeneration