Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PHIP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PHIP |
| Key Genes/Proteins | ANXA2, AND, MTOR, GLUT3, FN1, GBP2 |
| Related Diseases | Glioblastoma Invasion, Tumor, ALS, Glioblastoma, Als |
| Related Pathways | Immune Response |
Knowledge base pages for this entity
graph TD
PHIP["PHIP"]
PHIP -->|"modulates"| Glioblastoma_Invasion["Glioblastoma Invasion"]
PHIP -->|"regulates"| Tumor["Tumor"]
PHIP -->|"activates"| ALS["ALS"]
PHIP -->|"activates"| Glioblastoma["Glioblastoma"]
PHIP -->|"target for"| Als["Als"]
PHIP -->|"regulates"| ANXA2["ANXA2"]
PHIP -->|"regulates"| AND["AND"]
GENES["GENES"] -->|"regulates"| PHIP
GBM["GBM"] -->|"regulates"| PHIP
AKT["AKT"] -->|"activates"| PHIP
ASTROCYTE["ASTROCYTE"] -->|"activates"| PHIP
FN1["FN1"] -->|"regulates"| PHIP
MTOR["MTOR"] -->|"activates"| PHIP
ANXA2 -->|"regulates"| PHIP
GLUT3["GLUT3"] -->|"regulates"| PHIP| Target | Relation | Type | Str |
|---|---|---|---|
| Glioblastoma Invasion | modulates | phenotype | 0.80 |
| Tumor | regulates | disease | 0.65 |
| ALS | activates | disease | 0.65 |
| Glioblastoma | activates | disease | 0.65 |
| Als | therapeutic_target | disease | 0.65 |
| Glioblastoma | therapeutic_target | disease | 0.65 |
| ANXA2 | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| MTOR | activates | gene | 0.60 |
| GLUT3 | regulates | gene | 0.60 |
| FN1 | regulates | gene | 0.60 |
| GBP2 | regulates | gene | 0.60 |
| GLIOBLASTOMA | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
| Immune Response | activates | pathway | 0.60 |
| Mtor | activates | pathway | 0.60 |
| Pi3K/Akt | activates | pathway | 0.60 |
| Angiogenesis | activates | pathway | 0.60 |
| Epigenetic | activates | pathway | 0.60 |
| GLIOBLASTOMA | therapeutic_target | gene | 0.60 |
| Epigenetic | therapeutic_target | pathway | 0.60 |
| Immune Response | therapeutic_target | pathway | 0.60 |
| Mtor | therapeutic_target | pathway | 0.60 |
| Pi3K/Akt | therapeutic_target | pathway | 0.60 |
| Stem Cell | therapeutic_target | cell_type | 0.60 |
| Astrocyte | therapeutic_target | cell_type | 0.60 |
| GBM | regulates | gene | 0.60 |
| Radial Glia | therapeutic_target | cell_type | 0.60 |
| Akt | therapeutic_target | protein | 0.60 |
| Pi3K | therapeutic_target | protein | 0.60 |
| glioblastoma | regulates | disease | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| T cells | expressed_in | cell_type | 0.60 |
| Neural Stem Cell | expressed_in | cell_type | 0.55 |
| Stem Cell | expressed_in | cell_type | 0.55 |
| Astrocyte | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||