RPN1

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

RPN1 is a gene implicated in neurodegeneration research. Key relationships include: implicated in, activates, regulates. Associated with Cancer, Inflammation, Neuropathy. Connected to 18 entities in the SciDEX knowledge graph.

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graph TD
    RPN1["<b>RPN1</b>"]
    neurodegeneration{"neurodegeneration"}
    RPN1 -->|"implicated_in"| neurodegeneration
    AUTOPHAGY["AUTOPHAGY"]
    RPN1 -->|"implicated_in"| AUTOPHAGY
    PARKIN["PARKIN"]
    RPN1 -->|"regulates"| PARKIN
    Neuropathy{"Neuropathy"}
    RPN1 -->|"implicated_in"| Neuropathy
    Autophagy["Autophagy"]
    RPN1 -->|"implicated_in"| Autophagy
    Mitophagy["Mitophagy"]
    RPN1 -->|"regulates"| Mitophagy
    Differentiation["Differentiation"]
    RPN1 -->|"implicated_in"| Differentiation
    Unfolded_Protein_Response["Unfolded Protein Response"]
    RPN1 -->|"implicated_in"| Unfolded_Protein_Response
    Cancer{"Cancer"}
    RPN1 -->|"activates"| Cancer
    Inflammation{"Inflammation"}
    RPN1 -->|"activates"| Inflammation
    PINK1["PINK1"]
    PINK1 -->|"regulates"| RPN1
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"regulates"| RPN1
    AMPK["AMPK"]
    AMPK -->|"implicated_in"| RPN1
    RPL26["RPL26"]
    RPL26 -->|"regulates"| RPN1
    RPN2["RPN2"]
    RPN2 -->|"activates"| RPN1
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"activates"| RPN1
    CANCER["CANCER"]
    CANCER -->|"activates"| RPN1
    BCL_2["BCL-2"]
    BCL_2 -->|"activates"| RPN1
    style RPN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7