SCNN1A

Understanding Entity Pages

This page aggregates everything SciDEX knows about SCNN1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SCNN1A encodes the alpha subunit of the epithelial sodium channel (ENaC), involved in sodium homeostasis, fluid balance, and neuronal function

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graph TD
    SCNN1A["<b>SCNN1A</b>"]
    Cancer{"Cancer"}
    SCNN1A -->|"associated with"| Cancer
    CFTR["CFTR"]
    SCNN1A -->|"associated with"| CFTR
    PIEZO2["PIEZO2"]
    SCNN1A -->|"associated with"| PIEZO2
    TRPA1["TRPA1"]
    SCNN1A -->|"associated with"| TRPA1
    KCNMA1["KCNMA1"]
    SCNN1A -->|"associated with"| KCNMA1
    TRPV1["TRPV1"]
    SCNN1A -->|"associated with"| TRPV1
    KCNN4["KCNN4"]
    SCNN1A -->|"associated with"| KCNN4
    KCNQ1["KCNQ1"]
    SCNN1A -->|"associated with"| KCNQ1
    CACNA1C["CACNA1C"]
    SCNN1A -->|"associated with"| CACNA1C
    Oxidative_Phosphorylation(["Oxidative Phosphorylation"])
    SCNN1A -->|"associated with"| Oxidative_Phosphorylation
    Wnt(["Wnt"])
    SCNN1A -->|"associated with"| Wnt
    KCNK2["KCNK2"]
    SCNN1A -->|"associated with"| KCNK2
    PIEZO1["PIEZO1"]
    PIEZO1 -->|"associated with"| SCNN1A
    KCNK2 -->|"associated with"| SCNN1A
    SCN5A["SCN5A"]
    SCN5A -->|"associated with"| SCNN1A
    TRPM7["TRPM7"]
    TRPM7 -->|"associated with"| SCNN1A
    SCN1A["SCN1A"]
    SCN1A -->|"associated with"| SCNN1A
    TRPV4["TRPV4"]
    TRPV4 -->|"associated with"| SCNN1A
    CACNA1B["CACNA1B"]
    CACNA1B -->|"associated with"| SCNN1A
    CACNA1C -->|"associated with"| SCNN1A
    CFTR -->|"associated with"| SCNN1A
    KCNQ1 -->|"associated with"| SCNN1A
    TRPA1 -->|"associated with"| SCNN1A
    TRPV1 -->|"associated with"| SCNN1A
    style SCNN1A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0