TRPM7

Understanding Entity Pages

This page aggregates everything SciDEX knows about TRPM7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Transient Receptor Potential Cation Channel Subfamily M Member 7 - bifunctional channel-kinase

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flowchart TD
    TRPM7["TRPM7"] -->|"activates"| pyroptosis["pyroptosis"]
    TRPM7["TRPM7"] -->|"associated with"| status_epilepticus["status epilepticus"]
    STAT3["STAT3"] -->|"regulates"| TRPM7["TRPM7"]
    NS8593["NS8593"] -.->|"inhibits"| TRPM7["TRPM7"]
    TRPM7["TRPM7"] -->|"associated with"| Cancer["Cancer"]
    TRPM7["TRPM7"] -->|"activates"| Autoimmune["Autoimmune"]
    TRPM7["TRPM7"] -->|"activates"| Ms["Ms"]
    TRPM7["TRPM7"] -->|"activates"| Neuroinflammation["Neuroinflammation"]
    TRPM7["TRPM7"] -->|"activates"| Inflammation["Inflammation"]
    TRPM7["TRPM7"] -->|"associated with"| SCN1A["SCN1A"]
    TRPM7["TRPM7"] -->|"associated with"| TRPV4["TRPV4"]
    TRPM7["TRPM7"] -->|"associated with"| CACNA1B["CACNA1B"]
    style TRPM7 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style pyroptosis fill:#006494,stroke:#333,color:#e0e0e0
    style status_epilepticus fill:#ef5350,stroke:#333,color:#e0e0e0
    style STAT3 fill:#006494,stroke:#333,color:#e0e0e0
    style NS8593 fill:#6d3000,stroke:#333,color:#e0e0e0
    style Cancer fill:#ef5350,stroke:#333,color:#e0e0e0
    style Autoimmune fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ms fill:#ef5350,stroke:#333,color:#e0e0e0
    style Neuroinflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Inflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style SCN1A fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style TRPV4 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style CACNA1B fill:#4a1a6b,stroke:#333,color:#e0e0e0