KCNN4

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNN4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Comprehensive guide to KCNN4 (SK4, IK1) intermediate-conductance calcium-activated potassium channel in immune function, erythrocyte physiology, and neuroinflammation

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graph TD
    KCNN4["<b>KCNN4</b>"]
    Cancer{"Cancer"}
    KCNN4 -->|"associated with"| Cancer
    Carcinoma{"Carcinoma"}
    KCNN4 -->|"therapeutic target"| Carcinoma
    Ms{"Ms"}
    KCNN4 -->|"activates"| Ms
    Tumor{"Tumor"}
    KCNN4 -->|"activates"| Tumor
    KCNQ1["KCNQ1"]
    KCNN4 -->|"associated with"| KCNQ1
    CACNA1C["CACNA1C"]
    KCNN4 -->|"associated with"| CACNA1C
    Oxidative_Phosphorylation(["Oxidative Phosphorylation"])
    KCNN4 -->|"associated with"| Oxidative_Phosphorylation
    Wnt(["Wnt"])
    KCNN4 -->|"associated with"| Wnt
    KCNK2["KCNK2"]
    KCNN4 -->|"associated with"| KCNK2
    Axon_Guidance(["Axon Guidance"])
    KCNN4 -->|"associated with"| Axon_Guidance
    ERK["ERK"]
    KCNN4 -->|"therapeutic target"| ERK
    APOPTOSIS["APOPTOSIS"]
    KCNN4 -->|"activates"| APOPTOSIS
    PIEZO1["PIEZO1"]
    PIEZO1 -->|"associated with"| KCNN4
    KCNK2 -->|"associated with"| KCNN4
    SCN5A["SCN5A"]
    SCN5A -->|"associated with"| KCNN4
    TRPM7["TRPM7"]
    TRPM7 -->|"associated with"| KCNN4
    SCN1A["SCN1A"]
    SCN1A -->|"associated with"| KCNN4
    TRPV4["TRPV4"]
    TRPV4 -->|"associated with"| KCNN4
    CACNA1B["CACNA1B"]
    CACNA1B -->|"associated with"| KCNN4
    SCNN1A["SCNN1A"]
    SCNN1A -->|"associated with"| KCNN4
    CFTR["CFTR"]
    CFTR -->|"associated with"| KCNN4
    PIEZO2["PIEZO2"]
    PIEZO2 -->|"associated with"| KCNN4
    TRPA1["TRPA1"]
    TRPA1 -->|"associated with"| KCNN4
    KCNMA1["KCNMA1"]
    KCNMA1 -->|"associated with"| KCNN4
    style KCNN4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0