SYNPO

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNPO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SYNPO encodes synaptopodin, an actin-associated protein essential for spine apparatus formation, synaptic plasticity, and memory. Dysregulated in Alzheimer's disease and schizophrenia.

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graph TD
    SYNPO["<b>SYNPO</b>"]
    Als{"Als"}
    SYNPO -->|"interacts with"| Als
    ALS{"ALS"}
    SYNPO -->|"interacts with"| ALS
    Dendritic_Spine(["Dendritic Spine"])
    SYNPO -->|"associated with"| Dendritic_Spine
    Neuron["Neuron"]
    SYNPO -->|"expressed in"| Neuron
    neurodegeneration["neurodegeneration"]
    SYNPO -->|"implicated in"| neurodegeneration
    AND["AND"]
    AND -->|"associated with"| SYNPO
    style SYNPO fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0