XRCC1

Understanding Entity Pages

This page aggregates everything SciDEX knows about XRCC1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

XRCC1 is a gene implicated in neurodegeneration research. Key relationships include: activates, causes, interacts with. Associated with ALS, Als, Cancer. Connected to 26 entities in the SciDEX knowledge graph.

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graph TD
    XRCC1["<b>XRCC1</b>"]
    Cancer{"Cancer"}
    XRCC1 -->|"activates"| Cancer
    Als{"Als"}
    XRCC1 -->|"activates"| Als
    ALS{"ALS"}
    XRCC1 -->|"activates"| ALS
    NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"]
    XRCC1 -->|"activates"| NEURODEGENERATIVE_DISORDERS
    SETX["SETX"]
    XRCC1 -->|"activates"| SETX
    FEN1["FEN1"]
    XRCC1 -->|"activates"| FEN1
    CANCER["CANCER"]
    XRCC1 -->|"activates"| CANCER
    Neuron["Neuron"]
    XRCC1 -->|"expressed in"| Neuron
    neurodegeneration["neurodegeneration"]
    XRCC1 -->|"implicated in"| neurodegeneration
    SOX2["SOX2"]
    SOX2 -->|"interacts with"| XRCC1
    XPG["XPG"]
    XPG -->|"activates"| XRCC1
    SETX -->|"activates"| XRCC1
    TDP1["TDP1"]
    TDP1 -->|"activates"| XRCC1
    PNKP["PNKP"]
    PNKP -->|"activates"| XRCC1
    FEN1 -->|"activates"| XRCC1
    XPF["XPF"]
    XPF -->|"activates"| XRCC1
    DNA["DNA"]
    DNA -->|"activates"| XRCC1
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"activates"| XRCC1
    CANCER -->|"activates"| XRCC1
    AND["AND"]
    AND -->|"activates"| XRCC1
    NEURODEGENERATIVE_DISORDERS -->|"activates"| XRCC1
    style XRCC1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0