concept

XPR1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about XPR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

83Connections

0Hypotheses

0Analyses

46Outgoing

37Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	XPR1
Related Diseases	Primary Familial Brain Calcification, Basal Ganglia Calcifications, Ovarian Cancer, Parkinson, Als

Wiki Pages (6)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    XPR1["XPR1"]
    XPR1 -->|"causes"| Basal_Ganglia_Calcifications["Basal Ganglia Calcifications"]
    XPR1 -->|"regulates"| Ms["Ms"]
    XPR1 -->|"causes"| Als["Als"]
    XPR1 -->|"causes"| ALS["ALS"]
    XPR1 -->|"causes"| Fahr_disease["Fahr_disease"]
    XPR1 -->|"regulates"| SLC20A2["SLC20A2"]
    XPR1 -->|"regulates"| PDGFRB["PDGFRB"]
    XPR1 -->|"regulates"| PDGFB["PDGFB"]
    GENES["GENES"] -->|"regulates"| XPR1
    PDGFRB -->|"regulates"| XPR1
    PDGFB -->|"regulates"| XPR1
    SLC20A2 -->|"regulates"| XPR1
    AND["AND"] -->|"regulates"| XPR1

Outgoing (46)

Target	Relation	Type	Str
Primary Familial Brain Calcification	associated_with	disease	0.95
Primary Familial Brain Calcification	causes	disease	0.95
Basal Ganglia Calcifications	causes	disease	0.93
phosphate homeostasis	regulates	process	0.85
Ovarian Cancer	therapeutic_target	disease	0.85
Ovarian Cancer	associated_with	disease	0.85
Therapeutic Target	therapeutic_target	biomarker	0.85
Tumor Immune Cell Activity	modulates	process	0.75
Parkinson	associated_with	disease	0.65
Als	associated_with	disease	0.65
Aging	associated_with	disease	0.65
Ms	associated_with	disease	0.65
Ms	regulates	disease	0.65
ALS	associated_with	disease	0.65
Als	causes	disease	0.65
ALS	causes	disease	0.65
Fahr_disease	causes	disease	0.64
SLC20A2	associated_with	gene	0.60
SLC20A2	regulates	gene	0.60
Blood-Brain Barrier	associated_with	pathway	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
PARKINSON	associated_with	gene	0.60
PDGFRB	associated_with	gene	0.60
PDGFB	associated_with	gene	0.60
PDGFRB	regulates	gene	0.60
PDGFB	regulates	gene	0.60
CMPK2	associated_with	gene	0.60
JAM2	associated_with	gene	0.60
SCN10A	associated_with	gene	0.60
INPP4A	associated_with	gene	0.60
AND	causes	gene	0.60
P2RX7	associated_with	gene	0.60
AND	associated_with	gene	0.60
GENES	associated_with	gene	0.60
AND	regulates	gene	0.60
JUN	associated_with	gene	0.60
MYORG	associated_with	gene	0.60
Pdgf	associated_with	protein	0.60
Rb	associated_with	protein	0.60
Pdgf	regulates	protein	0.60
Rb	regulates	protein	0.60
App	causes	protein	0.60
Cerebellum	expressed_in	brain_region	0.55
White Matter	expressed_in	brain_region	0.55
Thalamus	expressed_in	brain_region	0.55
Basal Ganglia	expressed_in	brain_region	0.55

Incoming (37)

Source	Relation	Type	Str
JUN	associated_with	gene	0.60
JAM2	associated_with	gene	0.60
PDGFB	associated_with	gene	0.60
PDGFRB	associated_with	gene	0.60
GENES	associated_with	gene	0.60
GENES	regulates	gene	0.60
PDGFRB	regulates	gene	0.60
PDGFB	regulates	gene	0.60
SLC20A2	associated_with	gene	0.60
SLC20A2	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	associated_with	gene	0.60
PARKINSON	associated_with	gene	0.60
CMPK2	associated_with	gene	0.60
AND	associated_with	gene	0.60
MYORG	associated_with	gene	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
AND	regulates	gene	0.60
P2RX7	associated_with	gene	0.60
SCN10A	associated_with	gene	0.60
INPP4A	associated_with	gene	0.60
CMPK2	interacts_with	gene	0.60
JAM2	interacts_with	gene	0.60
MYORG	interacts_with	gene	0.60
PDGFB	interacts_with	gene	0.60
PDGFRB	interacts_with	gene	0.60
SLC20A2	interacts_with	gene	0.60
ADRA2A	associated_with	gene	0.60
CD36	associated_with	gene	0.60
MAP1A	associated_with	gene	0.60
NFE2L3	associated_with	gene	0.60
SIGLEC11	associated_with	gene	0.60
SLC24A4	associated_with	gene	0.60
SPINT1	associated_with	gene	0.60
CDC42EP3	associated_with	gene	0.60
FGFRL1	associated_with	gene	0.60
GRAMD1B	associated_with	gene	0.60
MYL9	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

XPR1

Understanding Entity Pages

Wiki Pages (6)

Unfolded Protein Response (UPR) Neurons

Primary Familial Brain Calcification (Fahr's Disease)

NFE2L3 Protein

MAP1A Gene