Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC24A4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SLC24A4 |
| Full Name | Solute Carrier Family 24 Member 4 |
| Aliases | Page for SLC24A4 Gene |
| Chromosome | 14q32.12 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain, Retina, Kidney, Placenta |
| UniProt ID | Q9NWA5 |
| NCBI Gene ID | 123041 |
| Ensembl ID | ENSG00000151148 |
| GeneCards | SLC24A4 |
| Human Protein Atlas | SLC24A4 |
| Associated Diseases | Ovarian Cancer |
| Interactions | SORL1, ZCWPW1, ABCA7, BIN1, CASS4, CD2AP |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["SLC24A4"]
N1["ABCA7"]
N1 -->|"interacts with"| N0
N2["BIN1"]
N2 -->|"interacts with"| N0
N3["CASS4"]
N3 -->|"interacts with"| N0
N4["CD2AP"]
N4 -->|"interacts with"| N0
N5["CD33"]
N5 -->|"interacts with"| N0
N6["CELF1"]
N6 -->|"interacts with"| N0
N7["CLU"]
N7 -->|"interacts with"| N0
N8["CR1"]
N8 -->|"interacts with"| N0
N9["Ovarian Cancer"]
N0 -->|"associated with"| N9
N10["Ovarian Cancer Progression"]
N0 -->|"involved in"| N10
N11["SORL1"]
N0 -->|"interacts with"| N11
N12["ZCWPW1"]
N0 -->|"interacts with"| N12
N13["SPINT1"]
N0 -->|"associated with"| N13
N14["XPR1"]
N0 -->|"associated with"| N14
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classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
classDef concept fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
classDef entity fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
class N0 gene
class N1 gene
class N2 gene
class N3 gene
class N4 gene
class N5 gene
class N6 gene
class N7 gene
class N8 gene
class N9 disease
class N10 process
class N11 gene
class N12 gene
class N13 gene
class N14 gene| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Ovarian Cancer | associated_with | disease | 0.73 |
| Ovarian Cancer Progression | involved_in | process | 0.72 |
| SORL1 | interacts_with | gene | 0.60 |
| ZCWPW1 | interacts_with | gene | 0.60 |
| SPINT1 | associated_with | gene | 0.60 |
| XPR1 | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:SLC24A4 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
| ABCA7 | interacts_with | gene | 0.60 |
| BIN1 | interacts_with | gene | 0.60 |
| CASS4 | interacts_with | gene | 0.60 |
| CD2AP | interacts_with | gene | 0.60 |
| CD33 | interacts_with | gene | 0.60 |
| CELF1 | interacts_with | gene | 0.60 |
| CLU | interacts_with | gene | 0.60 |
| CR1 | interacts_with | gene | 0.60 |
| EPHA1 | interacts_with | gene | 0.60 |
| FERMT2 | interacts_with | gene | 0.60 |
| INPP5D | interacts_with | gene | 0.60 |
| MEF2C | interacts_with | gene | 0.60 |
| NME8 | interacts_with | gene | 0.60 |
| PICALM | interacts_with | gene | 0.60 |
| PTK2B | interacts_with | gene | 0.60 |
| RIN3 | interacts_with | gene | 0.60 |
| ADRA2A | associated_with | gene | 0.60 |
| CD36 | associated_with | gene | 0.60 |
| MAP1A | associated_with | gene | 0.60 |
| NFE2L3 | associated_with | gene | 0.60 |
| SIGLEC11 | associated_with | gene | 0.60 |
| CDC42EP3 | associated_with | gene | 0.60 |
| FGFRL1 | associated_with | gene | 0.60 |
| MYL9 | associated_with | gene | 0.60 |
| HLA | interacts_with | gene | 0.60 |
| GRAMD1B | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:SLC24A4 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||