concept

BASAL GANGLIA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BASAL GANGLIA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

124Connections

0Hypotheses

0Analyses

41Outgoing

15Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	BASAL GANGLIA
Key Genes/Proteins	PARKIN, ACHE
Related Diseases	FRONTOTEMPORAL DEMENTIA, HUNTINGTON, HUNTINGTON'S, PARKINSON'S DISEASE, CANCER
Related Pathways	SYNAPTIC TRANSMISSION

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    BASAL_GANGLIA["BASAL GANGLIA"]
    BASAL_GANGLIA -->|"expressed in"| HUNTINGTON["HUNTINGTON"]
    BASAL_GANGLIA -->|"expressed in"| HUNTINGTON_S["HUNTINGTON'S"]
    BASAL_GANGLIA -->|"causes"| CANCER["CANCER"]
    BASAL_GANGLIA -->|"impairs"| PARKIN["PARKIN"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON["PARKINSON"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON_S["PARKINSON'S"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    BASAL_GANGLIA -->|"impairs"| SYNAPTIC_TRANSMISSION["SYNAPTIC TRANSMISSION"]
    zona_incerta["zona incerta"] -->|"interacts"| BASAL_GANGLIA
    ACHE["ACHE"] -->|"causes"| BASAL_GANGLIA
    OCLN["OCLN"] -->|"expressed in"| BASAL_GANGLIA
    GENES["GENES"] -->|"expressed in"| BASAL_GANGLIA
    XPR1["XPR1"] -->|"expressed in"| BASAL_GANGLIA
    SLC20A2["SLC20A2"] -->|"expressed in"| BASAL_GANGLIA
    PDGFRB["PDGFRB"] -->|"expressed in"| BASAL_GANGLIA
    PDGFB["PDGFB"] -->|"expressed in"| BASAL_GANGLIA

Outgoing (41)

Target	Relation	Type	Str
FRONTOTEMPORAL DEMENTIA	causes	disease	0.70
HUNTINGTON	expressed_in	disease	0.65
HUNTINGTON'S	expressed_in	disease	0.65
WHITE MATTER	activates	brain_region	0.65
CANCER	causes	disease	0.60
PARKIN	impairs	gene	0.60
PARKINSON	impairs	disease	0.60
PARKINSON'S	impairs	disease	0.60
PARKINSON'S DISEASE	impairs	disease	0.60
SYNAPTIC TRANSMISSION	impairs	biological_process	0.60
PARKIN	associated_with	gene	0.60
PARKINSON	associated_with	disease	0.60
WHITE MATTER	regulates	brain_region	0.50
DEMENTIA	associated_with	disease	0.50
DOPAMINE	associated_with	phenotype	0.50
STROKE	associated_with	disease	0.50
NEURON	associated_with	cell_type	0.50
SNCA	associated_with	gene	0.50
DRD2	associated_with	gene	0.50
HUNTINGTIN	associated_with	protein	0.45
ASTROGLIOSIS	associated_with	phenotype	0.45
NEURONS	associated_with	cell_type	0.45
TAU	associated_with	protein	0.45
ASTROCYTES	associated_with	cell_type	0.45
GABA	associated_with	phenotype	0.45
AMYLOID	associated_with	protein	0.45
NRF2	associated_with	gene	0.45
ATP13A2	associated_with	gene	0.45
TH	associated_with	gene	0.45
PARIETAL	co_discussed	brain_region	0.40
HUNTINGTON	co_discussed	disease	0.40
HUNTINGTON'S	co_discussed	disease	0.40
BRAINSTEM	co_discussed	brain_region	0.40
WHITE MATTER	co_discussed	brain_region	0.40
GRAY MATTER	expressed_in	brain_region	0.35
CORTEX	expressed_in	brain_region	0.35
BRAINSTEM	activates	brain_region	0.35
CANCER	activates	disease	0.35
CORPUS CALLOSUM	regulates	brain_region	0.35
SYNAPTIC TRANSMISSION	associated_with	process	0.35
PARKINSON'S DISEASE	associated_with	disease	0.35

Incoming (83)

Source	Relation	Type	Str
SUBSTANTIA NIGRA	causes	brain_region	0.65
PARKINSON'S DISEASE	degrades	disease	0.65
ACHE	causes	gene	0.60
FRONTOTEMPORAL DEMENTIA	associated_with	disease	0.50
ALPHA-SYNUCLEIN	associated_with	protein	0.50
DOPAMINERGIC NEURONS	associated_with	cell_type	0.50
NEURODEGENERATION	associated_with	phenotype	0.50
IRON ACCUMULATION	associated_with	phenotype	0.50
HUNTINGTON'S DISEASE	associated_with	disease	0.45
SYNAPTIC PLASTICITY	associated_with	phenotype	0.45
CEREBRAL AMYLOID ANGIOPATHY	associated_with	disease	0.45
MULTIPLE SCLEROSIS	associated_with	disease	0.45
DIMETHYL FUMARATE	associated_with	drug	0.45
CORTICOBASAL DEGENERATION	associated_with	disease	0.45
PROGRESSIVE SUPRANUCLEAR PALSY	associated_with	disease	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

BASAL GANGLIA

Understanding Entity Pages

Wiki Pages (20)

cbs-psp-daily-action-plan

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

Clinical Management Guide for CBS/PSP

Progressive Supranuclear Palsy (PSP)

Corticobasal Syndrome (CBS)

Novel Therapy Index

primary-progressive-aphasia

Atypical Parkinsonism

Device Therapies Comparison for CBS/PSP

calcium-dysregulation-comparison

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

Myoclonus and Cortical Hyperexcitability in Corticobasal Syndrome

PD Combination Therapy Matrix

Corticobasal Degeneration (CBD)

PI-2620 Tau PET in PSP

Section 162: Advanced Antioxidant and Redox Therapy in CBS/PSP

Neurons — Cell Type Hierarchy

CBS/PSP Treatment Rankings