gene 1,196 words KG: LCK 2026-03-24
kind:genesection:genesstate:published
Contents

LCK — LCK Proto-Oncogene, Src Family Tyrosine Kinase

🧬 Gene Info
Gene SymbolLCK
Full NameLCK Proto-Oncogene, Src Family Tyrosine Kinase
AliasesLymphocyte-Specific Protein Tyrosine Kinase
Chromosome1p35.2
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionT-lymphocytes and is essential for T-cell receptor (TCR) signaling, playing a critical role in adaptive immunity PMID: 15035502
Subcellular Localizationthe cytoplasmic face of the plasma membrane. It is one of the earliest signaling molecules activated following TCR engag
Molecular Weight56 kDa
Exons12
PathwaysNF-κB
NCBI Gene ID15035502
Ensembl IDENSG00000182866
GeneCardsLCK
Human Protein AtlasLCK
Associated DiseasesAging, Als, Alzheimer
InteractionsFYN, SRC, TCR, CD4, MAPK3, ZAP70
KG Connections67 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph