gene 2,702 words KG: TIMM17A
Contents

TIMM17A Gene

🧬 Gene Info
Gene SymbolTIMM17A
Full NameTranslocase of Inner Mitochondrial Membrane 17A
AliasesTIM17A, TIM17, Pdr3p
Chromosome1q32.1
Functionis an essential component of the TIM22 translocase complex located in the mitochondrial inner membrane.
Primary Expressionneuronal tissues
Molecular Weight~17 kDa
Amino Acids171 aa
Exons6
Gene TypeProtein coding
UniProt IDO60830 (TIM17_HUMAN)
NCBI Gene ID10628
Ensembl IDENSG00000139360
GeneCardsTIMM17A
Human Protein AtlasTIMM17A
Associated Diseasesneurodegeneration
InteractionsEIF2A, TFAM, ULK1, TIMM10, DNM1L, BNIP3
KG Connections43 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.61
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47

Related Analyses (2)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: inhibits
VDAC1 — Voltage Dependent Anion Channel 1
gene · KG edge: inhibits
ULK1 — UNC-51 Like Kinase 1
gene · KG edge: inhibits
TOMM20 — Translocase of Outer Mitochondrial Membrane 20
gene · KG edge: inhibits
TIMM9
gene · KG edge: inhibits

Knowledge Graph (12 edges)

TIMM17A inhibits EIF2A
TIMM17A inhibits TFAM
TIMM17A inhibits ULK1
TIMM17A inhibits TIMM10
TIMM17A inhibits DNM1L
TIMM17A inhibits Heart Failure
TIMM17A inhibits Ms
TIMM17A inhibits Unfolded Protein Response
TIMM17A inhibits Mitophagy
TIMM17A inhibits Mtor