concept

LOXL3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LOXL3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

101Connections

0Hypotheses

0Analyses

50Outgoing

28Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LOXL3
Related Diseases	Glioma
Related Pathways	Catalytic Motifs

Wiki Pages (1)

Knowledge base pages for this entity

Posterior Hypothalamic Area Neurons

cell · 722 words

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Pathway Diagram

graph TD
    LOXL3["LOXL3"]
    LOXL3 -->|"involved_in"| Cancer_Progression["Cancer Progression"]
    LOXL3 -->|"involved_in"| Extracellular_Matrix_Remodelin["Extracellular Matrix Remodeling"]
    LOXL3 -->|"involved_in"| Extracellular_Matrix["Extracellular Matrix"]
    LOXL3 -->|"involved_in"| Tissue_Homeostasis["Tissue Homeostasis"]
    LOXL3 -->|"regulates"| Innate_Immunity["Innate Immunity"]
    LOXL3 -->|"regulates"| Adaptive_Immunity["Adaptive Immunity"]
    LOXL3 -->|"expressed in"| Endostyle["Endostyle"]
    LOXL3 -->|"expressed in"| Liver["Liver"]
    LR_LOXL3["LR.LOXL3"] -->|"interacts"| LOXL3
    GENES["GENES"] -->|"target for"| LOXL3
    LOXL1_4["LOXL1-4"] -->|"expressed in"| LOXL3
    LOX["LOX"] -->|"inhibits"| LOXL3
    LOXL2["LOXL2"] -->|"expressed in"| LOXL3
    RNA["RNA"] -->|"expressed in"| LOXL3
    AND["AND"] -->|"inhibits"| LOXL3

Outgoing (73)

Target	Relation	Type	Str
Cancer Progression	involved_in	process	0.95
Extracellular Matrix Remodeling	involved_in	process	0.95
Extracellular Matrix	involved_in	process	0.95
Cancer Progression	promotes	process	0.95
Tissue Homeostasis	involved_in	process	0.92
Glioma	associated_with	disease	0.92
Innate Immunity	regulates	process	0.90
Adaptive Immunity	regulates	process	0.90
Endostyle	expressed_in	cell_type	0.90
Liver	expressed_in	cell_type	0.90
Vertebrate Immunity	involved_in	process	0.88
Glycolipid Metabolism	regulates	process	0.85
Immune-Metabolic Homeostasis	associated_with	process	0.85
Catalytic Motifs	associated_with	mechanism	0.85
Ecm Remodeling	involved_in	process	0.85
Phytohemagglutinin	upregulates	compound	0.85
Lipopolysaccharide	upregulates	compound	0.85
glycolipid metabolism	modulates	pathway	0.85
Metabolism	involved_in	process	0.82
Immunity	regulates	biological_process	0.80
PHA	modulates	compound	0.80
tumor progression	promotes	process	0.80
PHA	upregulates	compound	0.80
LOX	interacts_with	gene	0.80
LOXL1	interacts_with	gene	0.75
Ms	therapeutic_target	disease	0.65
Cancer	inhibits	disease	0.65
Tumor	therapeutic_target	disease	0.65
Als	implicated_in	disease	0.65
Tumor	expressed_in	disease	0.65
ALS	regulates	disease	0.65
Als	regulates	disease	0.65
CANCER	inhibits	gene	0.60
LOX	inhibits	gene	0.60
LOXL1	therapeutic_target	gene	0.60
AND	inhibits	gene	0.60
LOX/LOXL1-4	therapeutic_target	gene	0.60
LOXL2	therapeutic_target	gene	0.60
LOXL1-4	therapeutic_target	gene	0.60
LOX	regulates	gene	0.60
LOXL1	associated_with	gene	0.60
LR.LOXL3	implicated_in	gene	0.60
AND	regulates	gene	0.60
LOX/LOXL1-4	associated_with	gene	0.60
LOXL1-4	associated_with	gene	0.60
Lipid Metabolism	associated_with	pathway	0.60
Immune Response	associated_with	pathway	0.60
LOXL1	expressed_in	gene	0.60
LR.LOXL3	regulates	gene	0.60
LOXL1	stabilizes	gene	0.60

Incoming (28)

Source	Relation	Type	Str
LR.LOXL3	interacts_with	gene	0.85
GENES	therapeutic_target	gene	0.60
LOXL1-4	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
LOX	inhibits	gene	0.60
LOXL2	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
AND	inhibits	gene	0.60
LOX/LOXL1-4	expressed_in	gene	0.60
LOXL1-4	stabilizes	gene	0.60
LOX	regulates	gene	0.60
AND	regulates	gene	0.60
LOX/LOXL1-4	stabilizes	gene	0.60
LOX/LOXL1-4	therapeutic_target	gene	0.60
RNA	therapeutic_target	gene	0.60
LOX/LOXL1-4	associated_with	gene	0.60
LOXL1	expressed_in	gene	0.60
CANCER	inhibits	gene	0.60
LOXL1	stabilizes	gene	0.60
LR.LOXL3	regulates	gene	0.60
LOX	associated_with	gene	0.60
LOXL1	associated_with	gene	0.60
LOX	expressed_in	gene	0.60
GBM	co_expressed_with	gene	0.60
LOX	co_expressed_with	gene	0.60
LOXL1	co_expressed_with	gene	0.60
LOXL2	associated_with	gene	0.55
LOXL2	inhibits	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found