Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAS/RAF/MEK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | RAS/RAF/MEK |
Knowledge base pages for this entity
graph TD
RAS_RAF_MEK["RAS/RAF/MEK"]
Als["Als"] -->|"target for"| RAS_RAF_MEK
PTEN["PTEN"] -->|"contributes to"| RAS_RAF_MEK
ERK["ERK"] -->|"contributes to"| RAS_RAF_MEK
BRAF["BRAF"] -->|"target for"| RAS_RAF_MEK
PI3K["PI3K"] -->|"contributes to"| RAS_RAF_MEK
RAS["RAS"] -->|"contributes to"| RAS_RAF_MEK
CANCER["CANCER"] -->|"contributes to"| RAS_RAF_MEK
GENES["GENES"] -->|"contributes to"| RAS_RAF_MEK| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Als | therapeutic_target | disease | 0.70 |
| PTEN | contributes_to | gene | 0.60 |
| BRAF | therapeutic_target | gene | 0.60 |
| PI3K | contributes_to | gene | 0.60 |
| PIK3CA | contributes_to | gene | 0.60 |
| AKT | contributes_to | gene | 0.60 |
| OVERVIEW | therapeutic_target | gene | 0.60 |
| MTOR | contributes_to | gene | 0.60 |
| ERK | contributes_to | gene | 0.60 |
| RAS | contributes_to | gene | 0.60 |
| CANCER | contributes_to | gene | 0.60 |
| GENES | contributes_to | gene | 0.60 |
| Tumor | therapeutic_target | disease | 0.60 |
| Cancer | contributes_to | disease | 0.60 |
| Aging | therapeutic_target | disease | 0.60 |
| Breast Cancer | therapeutic_target | disease | 0.60 |
| Myeloma | therapeutic_target | disease | 0.60 |
| Lymphoma | therapeutic_target | disease | 0.60 |
| Lung Cancer | therapeutic_target | disease | 0.60 |
| ERK | therapeutic_target | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| RAS | therapeutic_target | gene | 0.60 |
| CANCER | therapeutic_target | gene | 0.60 |
| AUTOPHAGY | therapeutic_target | gene | 0.60 |
| Tumor | regulates | disease | 0.60 |
| Cancer | therapeutic_target | disease | 0.60 |
| ERK | associated_with | gene | 0.60 |
| AMPK | therapeutic_target | gene | 0.60 |
| RAS | associated_with | gene | 0.60 |
| CANCER | associated_with | gene | 0.60 |
| GENES | therapeutic_target | gene | 0.60 |
| Cancer | associated_with | disease | 0.60 |
| MEK | contributes_to | gene | 0.60 |
| MAPK | contributes_to | gene | 0.60 |
| RAF | contributes_to | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||