gene

GNA13

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GNA13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

56Connections
0Hypotheses
0Analyses
28Outgoing
28Incoming

Summary

GNA13 is a gene implicated in neurodegeneration research. Key relationships include: expressed in, associated with, implicated in. Associated with Als, Lymphoma, Schizophrenia. Connected to 23 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolGNA13
Full NameG Protein Subunit Alpha 13
Chromosome17q21.31
Protein FamilyGq alpha subunit family
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionneurons where it participates in synaptic transmission
Molecular Weight~43 kDa
Amino Acids377 aa
Exons11
UniProt ID[Q9UQF2](https://www.uniprot.org/uniprot/Q9UQF2)
Ensembl IDENSG00000127616
GeneCardsGNA13
Human Protein AtlasGNA13
Gene LocationChromosome 17q21.31
Exon Count11 exons spanning approximately 10 kb
Associated DiseasesAls, Schizophrenia
InteractionsGJA1, ROCK2, AND
KG Connections56 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

GNA13 Gene

gene · 584 words

ROCK2 Gene

gene · 2944 words

G Proteins

mechanism · 1607 words

GNA12 Gene

gene · 721 words

Gα13 Protein

protein · 559 words

Proteins

index · 296 words

Pathway Diagram

graph TD
    GNA13["<b>GNA13</b>"]
    Lymphoma{"Lymphoma"}
    GNA13 -->|"expressed in"| Lymphoma
    Als{"Als"}
    GNA13 -->|"expressed in"| Als
    GNA13 -->|"associated with"| Als
    Schizophrenia{"Schizophrenia"}
    GNA13 -->|"associated with"| Schizophrenia
    REL["REL"]
    GNA13 -->|"expressed in"| REL
    PRDM1["PRDM1"]
    GNA13 -->|"expressed in"| PRDM1
    Apoptosis(["Apoptosis"])
    GNA13 -->|"expressed in"| Apoptosis
    Nf__b(["Nf-Kappab"])
    GNA13 -->|"expressed in"| Nf__b
    GNAI1["GNAI1"]
    GNA13 -->|"associated with"| GNAI1
    GNA12["GNA12"]
    GNA13 -->|"associated with"| GNA12
    neurodegeneration["neurodegeneration"]
    GNA13 -->|"implicated in"| neurodegeneration
    CDKN2A["CDKN2A"]
    CDKN2A -->|"expressed in"| GNA13
    TP53["TP53"]
    TP53 -->|"expressed in"| GNA13
    TET2["TET2"]
    TET2 -->|"expressed in"| GNA13
    MYD88["MYD88"]
    MYD88 -->|"expressed in"| GNA13
    KMT2D["KMT2D"]
    KMT2D -->|"expressed in"| GNA13
    NF__B["NF-KappaB"]
    NF__B -->|"expressed in"| GNA13
    STAT3["STAT3"]
    STAT3 -->|"expressed in"| GNA13
    DDX3X["DDX3X"]
    DDX3X -->|"expressed in"| GNA13
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"expressed in"| GNA13
    RB1["RB1"]
    RB1 -->|"expressed in"| GNA13
    GRIN2B["GRIN2B"]
    GRIN2B -->|"associated with"| GNA13
    DISC1["DISC1"]
    DISC1 -->|"associated with"| GNA13
    style GNA13 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (28)

TargetRelationTypeStr
ROCK2interacts_withprotein0.80
Lymphomaexpressed_indisease0.65
Alsexpressed_indisease0.65
Alsassociated_withdisease0.65
Schizophreniaassociated_withdisease0.65

Incoming (28)

SourceRelationTypeStr
CDKN2Aexpressed_ingene0.60
TP53expressed_ingene0.60
TET2expressed_ingene0.60
MYD88expressed_ingene0.60
KMT2Dexpressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found