HFE

Understanding Entity Pages

This page aggregates everything SciDEX knows about HFE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

HFE is a protein involved in neurodegeneration research. Key relationships include: regulates, interacts with, expressed in. Associated with ALS, Als, Ischemia. Connected to 18 entities in the SciDEX knowledge graph.

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graph TD
    HFE["<b>HFE</b>"]
    Ischemia{"Ischemia"}
    HFE -->|"regulates"| Ischemia
    Ms{"Ms"}
    HFE -->|"interacts with"| Ms
    Als{"Als"}
    HFE -->|"regulates"| Als
    HFE -->|"associated with"| Als
    Tumor{"Tumor"}
    HFE -->|"interacts with"| Tumor
    ALS{"ALS"}
    HFE -->|"regulates"| ALS
    Endocytosis(["Endocytosis"])
    HFE -->|"regulates"| Endocytosis
    TFR1["TFR1"]
    HFE -->|"regulates"| TFR1
    JUN["JUN"]
    HFE -->|"regulates"| JUN
    MITOCHONDRIA["MITOCHONDRIA"]
    HFE -->|"regulates"| MITOCHONDRIA
    Neuron["Neuron"]
    HFE -->|"expressed in"| Neuron
    T_Cell["T Cell"]
    HFE -->|"expressed in"| T_Cell
    JUN -->|"regulates"| HFE
    TFR1 -->|"regulates"| HFE
    CAT["CAT"]
    CAT -->|"interacts with"| HFE
    TFR1 -->|"interacts with"| HFE
    MITOCHONDRIA -->|"regulates"| HFE
    AND["AND"]
    AND -->|"interacts with"| HFE
    style HFE fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0