TCF3

Understanding Entity Pages

This page aggregates everything SciDEX knows about TCF3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TCF3 is a gene implicated in neurodegeneration research. Key relationships include: activates, therapeutic target, regulates. Associated with Aging, Als, Alzheimer. Connected to 44 entities in the SciDEX knowledge graph.

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graph TD
    TCF3["<b>TCF3</b>"]
    Cancer{"Cancer"}
    TCF3 -->|"activates"| Cancer
    Carcinoma{"Carcinoma"}
    TCF3 -->|"activates"| Carcinoma
    TCF3 -->|"therapeutic target"| Cancer
    TCF3 -->|"therapeutic target"| Carcinoma
    Als{"Als"}
    TCF3 -->|"regulates"| Als
    Alzheimer{"Alzheimer"}
    TCF3 -->|"therapeutic target"| Alzheimer
    TCF3 -->|"regulates"| Cancer
    Aging{"Aging"}
    TCF3 -->|"activates"| Aging
    Ms{"Ms"}
    TCF3 -->|"activates"| Ms
    Leukemia{"Leukemia"}
    TCF3 -->|"activates"| Leukemia
    RRM1["RRM1"]
    TCF3 -->|"activates"| RRM1
    YBX1["YBX1"]
    TCF3 -->|"activates"| YBX1
    CTNNB1["CTNNB1"]
    CTNNB1 -->|"interacts with"| TCF3
    LRP1["LRP1"]
    LRP1 -->|"activates"| TCF3
    YBX1 -->|"activates"| TCF3
    LRP1 -->|"therapeutic target"| TCF3
    RRM1 -->|"activates"| TCF3
    MYC["MYC"]
    MYC -->|"regulates"| TCF3
    CDK9["CDK9"]
    CDK9 -->|"regulates"| TCF3
    TBX3["TBX3"]
    TBX3 -->|"regulates"| TCF3
    EP300["EP300"]
    EP300 -->|"activates"| TCF3
    FGFR3["FGFR3"]
    FGFR3 -->|"activates"| TCF3
    GENE_MUTATIONS["GENE MUTATIONS"]
    GENE_MUTATIONS -->|"activates"| TCF3
    CANCER["CANCER"]
    CANCER -->|"activates"| TCF3
    style TCF3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0