gene

DNAJC2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNAJC2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections
0Hypotheses
0Analyses
22Outgoing
7Incoming

Summary

Page for DNAJC2 - DnaJ Heat Shock Protein Family Member C2

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🧬 Gene Info
Gene SymbolDNAJC2
Full NameDnaJ Heat Shock Protein Family Member C2
AliasesPage for DNAJC2, Page for DNAJC2 Protein
Chromosome9p24.
Protein TypeChaperone
FunctionIn neurons, DNAJC2 participates in
Primary Expressionvarious brain regions:
Molecular Weight66.3 kDa
Amino Acids640 aa
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt ID[Q9Y2H5](https://www.uniprot.org/uniprot/Q9Y2H5)
Ensembl IDENSG00000137770
GeneCardsDNAJC2
Human Protein AtlasDNAJC2
Associated Diseasesneurodegeneration
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

DNAJC2 - DnaJ Heat Shock Protein Family Member C2

gene · 836 words

SLC24A2 — Solute Carrier Family 2 Member 4A2 (SLC24A2)

gene · 793 words

DNAJC2 Protein - DnaJ Heat Shock Protein Family Member C2

protein · 779 words

Proteins

index · 296 words

Genes

index · 271 words

Pathway Diagram

graph TD
    DNAJC2["<b>DNAJC2</b>"]
    Dementia{"Dementia"}
    DNAJC2 -->|"regulates"| Dementia
    Schizophrenia{"Schizophrenia"}
    DNAJC2 -->|"regulates"| Schizophrenia
    Alzheimer{"Alzheimer"}
    DNAJC2 -->|"regulates"| Alzheimer
    Multiple_Sclerosis{"Multiple Sclerosis"}
    DNAJC2 -->|"regulates"| Multiple_Sclerosis
    Als{"Als"}
    DNAJC2 -->|"regulates"| Als
    Cancer{"Cancer"}
    DNAJC2 -->|"regulates"| Cancer
    Ms{"Ms"}
    DNAJC2 -->|"regulates"| Ms
    CHMP3["CHMP3"]
    DNAJC2 -->|"regulates"| CHMP3
    PDE4C["PDE4C"]
    DNAJC2 -->|"regulates"| PDE4C
    BAG1["BAG1"]
    DNAJC2 -->|"associated with"| BAG1
    VTI1B["VTI1B"]
    DNAJC2 -->|"regulates"| VTI1B
    EIF4G1["EIF4G1"]
    DNAJC2 -->|"regulates"| EIF4G1
    NBN["NBN"]
    NBN -->|"regulates"| DNAJC2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"regulates"| DNAJC2
    SGK3["SGK3"]
    SGK3 -->|"regulates"| DNAJC2
    TNF["TNF"]
    TNF -->|"associated with"| DNAJC2
    CANCER["CANCER"]
    CANCER -->|"regulates"| DNAJC2
    SLC24A2["SLC24A2"]
    SLC24A2 -->|"regulates"| DNAJC2
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"regulates"| DNAJC2
    style DNAJC2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (22)

TargetRelationTypeStr
Dementiaregulatesdisease0.65
Schizophreniaregulatesdisease0.65
Alzheimerregulatesdisease0.65
Multiple Sclerosisregulatesdisease0.65
Alsregulatesdisease0.65

Incoming (7)

SourceRelationTypeStr
NBNregulatesgene0.60
SGK3regulatesgene0.60
TNFassociated_withgene0.60
SLC24A2regulatesgene0.60
ALZHEIMER'S DISEASEregulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found