BAG1

Understanding Entity Pages

This page aggregates everything SciDEX knows about BAG1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

BAG1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, expressed in, inhibits. Associated with Als, Alzheimer, Cancer. Connected to 42 entities in the SciDEX knowledge graph.

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graph TD
    BAG1["<b>BAG1</b>"]
    Als{"Als"}
    BAG1 -->|"expressed in"| Als
    Ms{"Ms"}
    BAG1 -->|"expressed in"| Ms
    Neurodegeneration{"Neurodegeneration"}
    BAG1 -->|"expressed in"| Neurodegeneration
    Dementia{"Dementia"}
    BAG1 -->|"regulates"| Dementia
    Schizophrenia{"Schizophrenia"}
    BAG1 -->|"regulates"| Schizophrenia
    Alzheimer{"Alzheimer"}
    BAG1 -->|"regulates"| Alzheimer
    Multiple_Sclerosis{"Multiple Sclerosis"}
    BAG1 -->|"regulates"| Multiple_Sclerosis
    BAG1 -->|"regulates"| Als
    Cancer{"Cancer"}
    BAG1 -->|"regulates"| Cancer
    BAG1 -->|"regulates"| Ms
    ASTROCYTES["ASTROCYTES"]
    BAG1 -->|"expressed in"| ASTROCYTES
    SOD1["SOD1"]
    BAG1 -->|"inhibits"| SOD1
    ICAM1["ICAM1"]
    ICAM1 -->|"inhibits"| BAG1
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"expressed in"| BAG1
    NBN["NBN"]
    NBN -->|"regulates"| BAG1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"regulates"| BAG1
    SGK3["SGK3"]
    SGK3 -->|"regulates"| BAG1
    TNF["TNF"]
    TNF -->|"associated with"| BAG1
    CANCER["CANCER"]
    CANCER -->|"regulates"| BAG1
    SLC24A2["SLC24A2"]
    SLC24A2 -->|"regulates"| BAG1
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"regulates"| BAG1
    DNAJC2["DNAJC2"]
    DNAJC2 -->|"associated with"| BAG1
    CHMP3["CHMP3"]
    CHMP3 -->|"regulates"| BAG1
    PDE4C["PDE4C"]
    PDE4C -->|"regulates"| BAG1
    style BAG1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0