gene 2,230 words KG: MYOT
Contents

MYOT Gene

🧬 Gene Info
Gene SymbolMYOT
Chromosome19q13.33
Functionis a gene encoding a Z-disc protein critical for sarcomere organization and maintenance.
Molecular Weight57 kDa
Amino Acids493 aa
Exons13
Pathwaysubiquitin-proteasome
Ensembl IDENSG00000136244
GeneCardsMYOT
Human Protein AtlasMYOT
Associated Diseasesmyofibrillar myopathy
InteractionsAUTOPHAGY, BRCA1, DES, DNAJB6, FLNC, GENES
KG Connections149 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (93)

Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
Score: 0.55
HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.54
Lysosomal Membrane Repair Enhancement
Score: 0.54
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Cryptic Exon Silencing Restoration
Score: 0.53
PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor
Score: 0.53
Vocal Cord Neuroplasticity Stimulation
Score: 0.52
Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.51
Microglia-Derived Extracellular Vesicle Engineering for Targ
Score: 0.48
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43
← Prevpg 5/5

Related Analyses (27)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

See Also (15)

ATP P2X3 Receptor Neurons
cell · KG edge: co_discussed
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: co_discussed
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
Genes
index · KG edge: activates
ABCD3 Gene
gene · KG edge: co_discussed

Knowledge Graph (12 edges)

MYOT causes myofibrillar myopathy
MYOT causes Myofibrillar Myopathy
BRCA1 degrades MYOT
DES degrades MYOT
DNAJB6 degrades MYOT
FLNC degrades MYOT
MYOT degrades NBR1
MYOT degrades P62
MYOT degrades SQSTM1
BRCA1 activates MYOT

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.