DLK1

Understanding Entity Pages

This page aggregates everything SciDEX knows about DLK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DLK1 (Delta-Like 1 Homolog) is a transmembrane protein involved in Notch signaling, cell fate decisions, neurodevelopment, and imprinted gene regulation.

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graph TD
    DLK1["<b>DLK1</b>"]
    Ms{"Ms"}
    DLK1 -->|"associated with"| Ms
    Als{"Als"}
    DLK1 -->|"associated with"| Als
    DLK1 -->|"interacts with"| Als
    Aging{"Aging"}
    DLK1 -->|"activates"| Aging
    ALS{"ALS"}
    DLK1 -->|"associated with"| ALS
    Epigenetic(["Epigenetic"])
    DLK1 -->|"associated with"| Epigenetic
    Dna_Methylation(["Dna Methylation"])
    DLK1 -->|"associated with"| Dna_Methylation
    GABRA1["GABRA1"]
    DLK1 -->|"associated with"| GABRA1
    DLK1 -->|"interacts with"| GABRA1
    DLK1 -->|"interacts with"| Dna_Methylation
    DLK1 -->|"interacts with"| Epigenetic
    ATG16L1["ATG16L1"]
    DLK1 -->|"inhibits"| ATG16L1
    GABRA1 -->|"associated with"| DLK1
    GAIN["GAIN"]
    GAIN -->|"associated with"| DLK1
    GENES["GENES"]
    GENES -->|"associated with"| DLK1
    DNA["DNA"]
    DNA -->|"associated with"| DLK1
    ATG12["ATG12"]
    ATG12 -->|"inhibits"| DLK1
    TFE3["TFE3"]
    TFE3 -->|"interacts with"| DLK1
    style DLK1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0