gene

DYNLL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DYNLL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections
0Hypotheses
0Analyses
25Outgoing
8Incoming

Summary

DYNLL1 Gene

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🧬 Gene Info
Gene SymbolDYNLL1
Full NameDynein Cytoplasmic 1 Light Chain 1
Chromosome12q12
FunctionDYNLL1 is a component of the dynein motor complex, essential for retrograde axonal transport.
UniProt ID[P63167](https://www.uniprot.org/uniprotkb/P63167/entry)
GeneCardsDYNLL1
Human Protein AtlasDYNLL1
Associated DiseasesAlzheimer's disease, Charcot-Marie-Tooth disease
Known Drugs/Compoundsrapamycin
InteractionsEIF4EBP1, GAPDH, HOMER1, JNK1, LAMP1, LC3
KG Connections33 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (9)

Knowledge base pages for this entity

Canonical Page

DYNLL1 Gene

gene · 642 words

Dynein Motor Protein

mechanism · 2466 words

DYNLT1 — Dynein Light Chain Tctex-Type 1

gene · 2182 words

Advanced Cytoskeletal Dynamics Modulator Therapy for Neurodegeneration

therapeutic · 2072 words

DYNLRB1 Gene

gene · 666 words

Dynein — Cytoplasmic Dynein 1

protein · 629 words

Pathway Diagram

flowchart TD
    N0["DYNLL1"]
    N1["EIF4EBP1"]
    N0 -->|"activates"| N1
    N2["GAPDH"]
    N0 -->|"activates"| N2
    N3["GFP"]
    N0 -->|"activates"| N3
    N4["GLUT4"]
    N0 -->|"activates"| N4
    N5["HOMER1"]
    N0 -->|"activates"| N5
    N6["JNK1"]
    N0 -->|"activates"| N6
    N7["LAMP1"]
    N0 -->|"activates"| N7
    N8["LC3"]
    N0 -->|"activates"| N8

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    class N0 gene
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene

Outgoing (25)

TargetRelationTypeStr
EIF4EBP1activatesgene0.60
GAPDHactivatesgene0.60
HOMER1activatesgene0.60
JNK1activatesgene0.60
LAMP1activatesgene0.60

Incoming (8)

SourceRelationTypeStr
ATG5activatesgene0.60
ATMactivatesgene0.60
ATRactivatesgene0.60
CASP3activatesgene0.60
CTSBactivatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found