gene

HSPA6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HSPA6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

36Connections
0Hypotheses
0Analyses
27Outgoing
9Incoming
0Experiments

Summary

HSPA6 is a gene implicated in neurodegeneration research. Key relationships include: expressed in, implicated in. Associated with Cancer, Lymphoma, Ms. Connected to 28 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolHSPA6
Protein TypeChaperone
FunctionHSPA6 (Heat Shock Protein Family A (Hsp70) Member 6) is a member of the Hsp70 family of molecular chaperones.
Primary Expressionvarious cancers:
PathwaysApoptosis, Unfolded Protein Response, Nf-Κb, Phagocytosis
Ensembl IDENSG00000173110
GeneCardsHSPA6
Human Protein AtlasHSPA6
Associated Diseasesneurodegeneration
KG Connections36 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

HSPA6

gene · 791 words

DnaJ Heat Shock Protein Family (Hsp40) Member C7

gene · 883 words

DNAJA2

gene · 845 words

BAG2

gene · 757 words

HSPBP1

gene · 673 words

Genes

index · 271 words

Pathway Diagram

graph TD
    HSPA6["<b>HSPA6</b>"]
    Lymphoma{"Lymphoma"}
    HSPA6 -->|"expressed in"| Lymphoma
    Ms{"Ms"}
    HSPA6 -->|"expressed in"| Ms
    Cancer{"Cancer"}
    HSPA6 -->|"expressed in"| Cancer
    Tumor{"Tumor"}
    HSPA6 -->|"expressed in"| Tumor
    DNAJB1["DNAJB1"]
    HSPA6 -->|"expressed in"| DNAJB1
    IKBKB["IKBKB"]
    HSPA6 -->|"expressed in"| IKBKB
    HSPA1B["HSPA1B"]
    HSPA6 -->|"expressed in"| HSPA1B
    HSPE1["HSPE1"]
    HSPA6 -->|"expressed in"| HSPE1
    HSP90AB1["HSP90AB1"]
    HSPA6 -->|"expressed in"| HSP90AB1
    HSP70["HSP70"]
    HSPA6 -->|"expressed in"| HSP70
    PHAGOCYTOSIS["PHAGOCYTOSIS"]
    HSPA6 -->|"expressed in"| PHAGOCYTOSIS
    HSPH1["HSPH1"]
    HSPA6 -->|"expressed in"| HSPH1
    UBIQUITIN["UBIQUITIN"]
    UBIQUITIN -->|"expressed in"| HSPA6
    CANCER["CANCER"]
    CANCER -->|"expressed in"| HSPA6
    BAG3["BAG3"]
    BAG3 -->|"expressed in"| HSPA6
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"expressed in"| HSPA6
    UBC["UBC"]
    UBC -->|"expressed in"| HSPA6
    HSPD1["HSPD1"]
    HSPD1 -->|"expressed in"| HSPA6
    NF__B["NF-KappaB"]
    NF__B -->|"expressed in"| HSPA6
    DNAJC7["DNAJC7"]
    DNAJC7 -->|"expressed in"| HSPA6
    style HSPA6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (27)

TargetRelationTypeStr
Lymphomaexpressed_indisease0.65
Msexpressed_indisease0.65
Cancerexpressed_indisease0.65
Tumorexpressed_indisease0.65
DNAJB1expressed_ingene0.60

Incoming (9)

SourceRelationTypeStr
UBIQUITINexpressed_ingene0.60
BAG3expressed_ingene0.60
UBCexpressed_ingene0.60
HSPD1expressed_ingene0.60
DNAJC7expressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found