CATHEPSIN B

Understanding Entity Pages

This page aggregates everything SciDEX knows about CATHEPSIN B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Cathepsin B, lysosomal protease in neurodegeneration

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graph TD
    CATHEPSIN_B["<b>CATHEPSIN B</b>"]
    ATG7["ATG7"]
    CATHEPSIN_B -->|"activates"| ATG7
    TUBULIN["TUBULIN"]
    CATHEPSIN_B -->|"activates"| TUBULIN
    SYNAPSIN_I["SYNAPSIN I"]
    CATHEPSIN_B -->|"activates"| SYNAPSIN_I
    ALZHEIMER["ALZHEIMER"]
    CATHEPSIN_B -->|"activates"| ALZHEIMER
    Genes["Genes"]
    CATHEPSIN_B -->|"activates"| Genes
    LYSOSOME["LYSOSOME"]
    CATHEPSIN_B -->|"activates"| LYSOSOME
    Alzheimer_Disease["Alzheimer Disease"]
    CATHEPSIN_B -->|"activates"| Alzheimer_Disease
    disease["disease"]
    CATHEPSIN_B -->|"activates"| disease
    DMSO["DMSO"]
    CATHEPSIN_B -->|"activates"| DMSO
    PRKAA["PRKAA"]
    CATHEPSIN_B -->|"activates"| PRKAA
    Infection["Infection"]
    CATHEPSIN_B -->|"activates"| Infection
    Proteins["Proteins"]
    CATHEPSIN_B -->|"activates"| Proteins
    RAPAMYCIN["RAPAMYCIN"]
    CATHEPSIN_B -->|"activates"| RAPAMYCIN
    AUTOPHAGOSOME["AUTOPHAGOSOME"]
    CATHEPSIN_B -->|"activates"| AUTOPHAGOSOME
    Proteins["Proteins"]
    CATHEPSIN_B -->|"expressed in"| Proteins
    TFEB["TFEB"]
    TFEB -->|"activates"| CATHEPSIN_B
    ACTB["ACTB"]
    ACTB -->|"activates"| CATHEPSIN_B
    Autophagy["Autophagy"]
    Autophagy -->|"activates"| CATHEPSIN_B
    CTSD["CTSD"]
    CTSD -->|"activates"| CATHEPSIN_B
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"activates"| CATHEPSIN_B
    mTOR["mTOR"]
    mTOR -->|"activates"| CATHEPSIN_B
    MAP1LC3B["MAP1LC3B"]
    MAP1LC3B -->|"activates"| CATHEPSIN_B
    SYT1["SYT1"]
    SYT1 -->|"activates"| CATHEPSIN_B
    MAP2["MAP2"]
    MAP2 -->|"activates"| CATHEPSIN_B
    SNAP25["SNAP25"]
    SNAP25 -->|"activates"| CATHEPSIN_B
    TUBB3["TUBB3"]
    TUBB3 -->|"activates"| CATHEPSIN_B
    CTSB["CTSB"]
    CTSB -->|"activates"| CATHEPSIN_B
    SYN1["SYN1"]
    SYN1 -->|"activates"| CATHEPSIN_B
    RIBOSOMAL_PROTEIN_S6["RIBOSOMAL PROTEIN S6"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| CATHEPSIN_B
    LAMP1["LAMP1"]
    LAMP1 -->|"activates"| CATHEPSIN_B