MSH2

Understanding Entity Pages

This page aggregates everything SciDEX knows about MSH2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MSH2 is a protein involved in neurodegeneration research. Key relationships include: expressed in, associated with, causes. Associated with Als, Cancer, Colorectal Cancer. Connected to 50 entities in the SciDEX knowledge graph.

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graph TD
    MSH2["<b>MSH2</b>"]
    Cancer{"Cancer"}
    MSH2 -->|"expressed in"| Cancer
    Tumor{"Tumor"}
    MSH2 -->|"expressed in"| Tumor
    Ms{"Ms"}
    MSH2 -->|"expressed in"| Ms
    PI3K["PI3K"]
    MSH2 -->|"expressed in"| PI3K
    RB1["RB1"]
    MSH2 -->|"expressed in"| RB1
    MSH6["MSH6"]
    MSH2 -->|"expressed in"| MSH6
    GENES["GENES"]
    MSH2 -->|"expressed in"| GENES
    DNA["DNA"]
    MSH2 -->|"expressed in"| DNA
    ATRX["ATRX"]
    MSH2 -->|"expressed in"| ATRX
    AKT["AKT"]
    MSH2 -->|"expressed in"| AKT
    TP53["TP53"]
    MSH2 -->|"expressed in"| TP53
    MLH1["MLH1"]
    MSH2 -->|"expressed in"| MLH1
    TP53 -->|"expressed in"| MSH2
    GENES -->|"expressed in"| MSH2
    RB1 -->|"expressed in"| MSH2
    ATRX -->|"expressed in"| MSH2
    AKT -->|"expressed in"| MSH2
    DNA -->|"expressed in"| MSH2
    PI3K -->|"expressed in"| MSH2
    MLH1 -->|"expressed in"| MSH2
    style MSH2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0