NDUFA9

Understanding Entity Pages

This page aggregates everything SciDEX knows about NDUFA9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene encoding a core subunit of mitochondrial Complex I (NADH:ubiquinone oxidoreductase), essential for oxidative phosphorylation and implicated in Leigh syndrome and Parkinson's disease.

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graph TD
    NDUFA9["<b>NDUFA9</b>"]
    Parkinson_s_Disease{"Parkinson's Disease"}
    NDUFA9 -->|"associated with"| Parkinson_s_Disease
    Alzheimer{"Alzheimer"}
    NDUFA9 -->|"associated with"| Alzheimer
    Ms{"Ms"}
    NDUFA9 -->|"regulates"| Ms
    Parkinson{"Parkinson"}
    NDUFA9 -->|"regulates"| Parkinson
    Huntington{"Huntington"}
    NDUFA9 -->|"associated with"| Huntington
    NDUFA9 -->|"associated with"| Parkinson
    Prion_Disease{"Prion Disease"}
    NDUFA9 -->|"associated with"| Prion_Disease
    Pi3K(["Pi3K"])
    NDUFA9 -->|"regulates"| Pi3K
    Akt(["Akt"])
    NDUFA9 -->|"regulates"| Akt
    TUBB["TUBB"]
    NDUFA9 -->|"associated with"| TUBB
    PI3K["PI3K"]
    NDUFA9 -->|"regulates"| PI3K
    GENES["GENES"]
    NDUFA9 -->|"associated with"| GENES
    TUBB -->|"associated with"| NDUFA9
    SNCA["SNCA"]
    SNCA -->|"associated with"| NDUFA9
    TUBB3["TUBB3"]
    TUBB3 -->|"associated with"| NDUFA9
    SLC6A3["SLC6A3"]
    SLC6A3 -->|"associated with"| NDUFA9
    TUBB4B["TUBB4B"]
    TUBB4B -->|"associated with"| NDUFA9
    AKT["AKT"]
    AKT -->|"associated with"| NDUFA9
    PI3K -->|"regulates"| NDUFA9
    AKT -->|"regulates"| NDUFA9
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| NDUFA9
    AND["AND"]
    AND -->|"associated with"| NDUFA9
    GENES -->|"associated with"| NDUFA9
    style NDUFA9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0