gene

TBC1D24

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TBC1D24: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

67Connections

0Hypotheses

0Analyses

46Outgoing

21Incoming

0Experiments

Summary

Page for TBC1D24 Gene

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🧬 Gene Info

Gene Symbol	TBC1D24
Full Name	TBC1D24
Aliases	KIAA0431, FAM57B [@wang2019]
Chromosome	16p13.3 [@zhang2019]
Protein Type	Gene
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the brain and plays critical roles in synaptic vesicle trafficking, endolysosomal trafficking, and neuronal development
Molecular Weight	67.8 kDa
Amino Acids	572 aa
Exons	4
UniProt ID	Q9P2R3
NCBI Gene ID	201299
Ensembl ID	ENSG00000148926
GeneCards	TBC1D24
Human Protein Atlas	TBC1D24
Associated Diseases	neurodegeneration
Interactions	PLIN4
KG Connections	67 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TBC1D24 — AlphaFold Q9P2R3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    TBC1D24["<b>TBC1D24</b>"]
    Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    TBC1D24 -->|"expressed in"| Amyotrophic_Lateral_Sclerosis
    Als["Als"]
    TBC1D24 -->|"expressed in"| Als
    Dementia["Dementia"]
    TBC1D24 -->|"expressed in"| Dementia
    Frontotemporal_Dementia["Frontotemporal Dementia"]
    TBC1D24 -->|"expressed in"| Frontotemporal_Dementia
    MAPT["MAPT"]
    TBC1D24 -->|"expressed in"| MAPT
    NEURON["NEURON"]
    TBC1D24 -->|"expressed in"| NEURON
    DEMENTIA["DEMENTIA"]
    TBC1D24 -->|"expressed in"| DEMENTIA
    CDKN1A["CDKN1A"]
    TBC1D24 -->|"expressed in"| CDKN1A
    TIA1["TIA1"]
    TBC1D24 -->|"expressed in"| TIA1
    FUS["FUS"]
    TBC1D24 -->|"expressed in"| FUS
    Er_Stress["Er Stress"]
    TBC1D24 -->|"expressed in"| Er_Stress
    Apoptosis["Apoptosis"]
    TBC1D24 -->|"expressed in"| Apoptosis
    Neuron["Neuron"]
    TBC1D24 -->|"expressed in"| Neuron
    PLIN4["PLIN4"]
    TBC1D24 -->|"expressed in"| PLIN4
    ATXN2["ATXN2"]
    TBC1D24 -->|"expressed in"| ATXN2
    HNRNPA2B1["HNRNPA2B1"]
    TBC1D24 -->|"expressed in"| HNRNPA2B1
    BID["BID"]
    TBC1D24 -->|"expressed in"| BID
    HNRNPA1["HNRNPA1"]
    TBC1D24 -->|"expressed in"| HNRNPA1
    ALS["ALS"]
    TBC1D24 -->|"expressed in"| ALS
    CCNF["CCNF"]
    TBC1D24 -->|"expressed in"| CCNF
    TDP_43["TDP-43"]
    TBC1D24 -->|"expressed in"| TDP_43
    TPRKB["TPRKB"]
    TBC1D24 -->|"expressed in"| TPRKB
    AND["AND"]
    TBC1D24 -->|"expressed in"| AND
    APOPTOSIS["APOPTOSIS"]
    TBC1D24 -->|"expressed in"| APOPTOSIS
    SMN["SMN"]
    TBC1D24 -->|"expressed in"| SMN
    GENES["GENES"]
    TBC1D24 -->|"expressed in"| GENES
    AMYOTROPHIC_LATERAL_SCLEROSIS["AMYOTROPHIC LATERAL SCLEROSIS"]
    TBC1D24 -->|"expressed in"| AMYOTROPHIC_LATERAL_SCLEROSIS
    CNTN4["CNTN4"]
    TBC1D24 -->|"expressed in"| CNTN4
    Tdp_43["Tdp-43"]
    TBC1D24 -->|"expressed in"| Tdp_43
    Cell_Cycle["Cell Cycle"]
    TBC1D24 -->|"expressed in"| Cell_Cycle

Outgoing (46)

Target	Relation	Type	Str
Spinal Muscular Atrophy	expressed_in	disease	0.65
Amyotrophic Lateral Sclerosis	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
Dementia	expressed_in	disease	0.65
Frontotemporal Dementia	expressed_in	disease	0.65
Frontotemporal Dementia	encodes	disease	0.65
Dementia	encodes	disease	0.65
Amyotrophic Lateral Sclerosis	encodes	disease	0.65
Als	encodes	disease	0.65
MAPT	expressed_in	gene	0.60
CDKN1A	expressed_in	gene	0.60
TIA1	expressed_in	gene	0.60
FUS	expressed_in	gene	0.60
PLIN4	expressed_in	gene	0.60
ATXN2	expressed_in	gene	0.60
HNRNPA2B1	expressed_in	gene	0.60
BID	expressed_in	gene	0.60
HNRNPA1	expressed_in	gene	0.60
CCNF	expressed_in	gene	0.60
TDP-43	expressed_in	gene	0.60
SMN	expressed_in	gene	0.60
CNTN4	expressed_in	gene	0.60
BID	encodes	gene	0.60
NEURON	expressed_in	gene	0.60
DEMENTIA	expressed_in	gene	0.60
Er Stress	expressed_in	pathway	0.60
Apoptosis	expressed_in	pathway	0.60
Neuron	expressed_in	cell_type	0.60
ALS	expressed_in	gene	0.60
TPRKB	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	expressed_in	gene	0.60
Tdp-43	expressed_in	pathway	0.60
Cell Cycle	expressed_in	pathway	0.60
Er Stress	encodes	pathway	0.60
Cell Cycle	encodes	pathway	0.60
Apoptosis	encodes	pathway	0.60
Neuron	encodes	cell_type	0.60
Tdp-43	encodes	protein	0.60
Raf	expressed_in	protein	0.60
Ca1	expressed_in	brain_region	0.55
Spinal Cord	expressed_in	brain_region	0.55
Cerebellum	expressed_in	brain_region	0.55
PLIN4	activates	gene	0.50

Incoming (21)

Source	Relation	Type	Str
ATXN2	expressed_in	gene	0.60
HNRNPA1	expressed_in	gene	0.60
CNTN4	expressed_in	gene	0.60
PLIN4	expressed_in	gene	0.60
BID	expressed_in	gene	0.60
HNRNPA2B1	expressed_in	gene	0.60
TDP-43	expressed_in	gene	0.60
FUS	encodes	gene	0.60
HNRNPA2B1	encodes	gene	0.60
ATXN2	encodes	gene	0.60
HNRNPA1	encodes	gene	0.60
CNTN4	encodes	gene	0.60
SMN	encodes	gene	0.60
CCNF	encodes	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
ALS	expressed_in	gene	0.60
NEURON	encodes	gene	0.60
ALS	encodes	gene	0.60
DEMENTIA	encodes	gene	0.60
TPRKB	encodes	gene	0.60
APOPTOSIS	encodes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

TBC1D24

Understanding Entity Pages

Summary

Wiki Pages (6)

TBC1D24 Gene

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TBC1D24 Protein

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