U2AF1

Understanding Entity Pages

This page aggregates everything SciDEX knows about U2AF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

U2AF1 is a gene implicated in neurodegeneration research. Key relationships include: activates, associated with, therapeutic target. Associated with Als, Alzheimer, Breast Cancer. Connected to 45 entities in the SciDEX knowledge graph.

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graph TD
    U2AF1["<b>U2AF1</b>"]
    Cancer{"Cancer"}
    U2AF1 -->|"therapeutic target"| Cancer
    Cardiovascular{"Cardiovascular"}
    U2AF1 -->|"therapeutic target"| Cardiovascular
    Inflammation{"Inflammation"}
    U2AF1 -->|"activates"| Inflammation
    Alzheimer{"Alzheimer"}
    U2AF1 -->|"therapeutic target"| Alzheimer
    Heart_Failure{"Heart Failure"}
    U2AF1 -->|"therapeutic target"| Heart_Failure
    U2AF1 -->|"associated with"| Alzheimer
    U2AF1 -->|"associated with"| Cardiovascular
    U2AF1 -->|"associated with"| Heart_Failure
    Osteoporosis{"Osteoporosis"}
    U2AF1 -->|"associated with"| Osteoporosis
    U2AF1 -->|"activates"| Heart_Failure
    U2AF1 -->|"activates"| Alzheimer
    U2AF1 -->|"activates"| Cancer
    ASXL1["ASXL1"]
    ASXL1 -->|"activates"| U2AF1
    SF3B1["SF3B1"]
    SF3B1 -->|"activates"| U2AF1
    TET2["TET2"]
    TET2 -->|"activates"| U2AF1
    TP53["TP53"]
    TP53 -->|"activates"| U2AF1
    DNMT3A["DNMT3A"]
    DNMT3A -->|"activates"| U2AF1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"activates"| U2AF1
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"activates"| U2AF1
    AND["AND"]
    AND -->|"activates"| U2AF1
    GENES["GENES"]
    GENES -->|"activates"| U2AF1
    DNA["DNA"]
    DNA -->|"activates"| U2AF1
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"activates"| U2AF1
    CANCER["CANCER"]
    CANCER -->|"activates"| U2AF1
    style U2AF1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0