concept

YAP/TAZ

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about YAP/TAZ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections
0Hypotheses
0Analyses
1Outgoing
2Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameYAP/TAZ
Key Genes/ProteinsPIEZO1

Wiki Pages (20)

Knowledge base pages for this entity

Corticobasal Syndrome (CBS)

disease · 11374 words

Novel Therapy Index

idea · 10647 words

TEAD1 — TEA Domain Transcription Factor 1

gene · 3104 words

TAZ (WWTR1)

gene · 3051 words

DVL3 — Dishevelled Segment Polarity Protein 3

gene · 2849 words

Pathway Diagram

graph TD
    YAP_TAZ["YAP/TAZ"]
    TAZ["TAZ"] -->|"inhibits"| YAP_TAZ
    YAP["YAP"] -->|"inhibits"| YAP_TAZ
    Breast_Cancer["Breast Cancer"] -->|"activates"| YAP_TAZ
    HIPPO["HIPPO"] -->|"regulates"| YAP_TAZ
    UBIQUITIN["UBIQUITIN"] -->|"regulates"| YAP_TAZ
    LATS1["LATS1"] -->|"regulates"| YAP_TAZ
    Cancer["Cancer"] -->|"regulates"| YAP_TAZ
    Als["Als"] -->|"regulates"| YAP_TAZ

Outgoing (1)

TargetRelationTypeStr
cell homeostasismaintainsprocess0.85

Incoming (45)

SourceRelationTypeStr
HIPPOregulatesconcept0.50
PIEZO1protects_againstgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found