| Gene Symbol | FIP200 |
| Chromosome | 6q24.2 |
| Protein Type | Scaffold Protein |
| Function | is a 200 kDa scaffold protein that plays essential roles in autophagy initiation, cell adhesion, migration, and neuronal survival. |
| Molecular Weight | 200 kDa |
| Amino Acids | 664 aa |
| Pathways | Akt, Apoptosis, Autophagy, Wnt, autophagy |
| Ensembl ID | ENSG00000048991 |
| GeneCards | FIP200 |
| Human Protein Atlas | FIP200 |
| Mitochondrial quality control | Removing damaged mitochondria through mitophagy |
| Protein aggregate clearance | Degrading misfolded proteins and aggregates |
| Synaptic maintenance | Regulating synaptic vesicle recycling and neurotransmitter release |
| Neuronal survival | Preventing apoptosis under cellular stress |
| Associated Diseases | AD, ALI, ALS, Alzheimer, Cancer |
| Known Drugs/Compounds | rapamycin |
| Interactions | RTN3, SESN2, AMBRA1, APC, PEX3, PTEN |
| KG Connections | 1107 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |