| Gene Symbol | TREH |
| Full Name | Trehalase |
| Chromosome | 11q23.3 |
| Function | is a non-reducing disaccharide found in many organisms, where it serves as a protectant against various environmental stresses. |
| Primary Expression | the small intestine, kidney, liver, and brain |
| Subcellular Localization | the cytosol |
| Molecular Weight | 65 kDa |
| Amino Acids | 583 aa |
| Pathways | Autophagy, Chaperone, Tdp-43, autophagy pathway, oxidative stress response |
| UniProt ID | [Q9NUH0](https://www.uniprot.org/uniprot/Q9NUH0) |
| Ensembl ID | ENSG00000143537 |
| GeneCards | TREH |
| Human Protein Atlas | TREH |
| Molecular weight | ~65 kDa (membrane form) |
| Catalytic domain | GH37 signature motifs |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma, Parkinson |
| Known Drugs/Compounds | rapamycin |
| Interactions | ATG10, ATG12, TFEB, CALCINEURIN, HSPB8, CTSB |
| KG Connections | 181 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |