concept

EOMES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EOMES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

30Outgoing

16Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	EOMES
Summary	Page for Intermediate Progenitor Cells
Key Genes/Proteins	B7S1, PD-1, PD-L1, CANCER, CD8, AND
Related Diseases	Tumor, Cancer, ALS, Carcinoma, Als
Related Pathways	Immune Response

Wiki Pages (10)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    EOMES["EOMES"]
    EOMES -->|"activates"| Tumor["Tumor"]
    EOMES -->|"activates"| Cancer["Cancer"]
    EOMES -->|"activates"| ALS["ALS"]
    EOMES -->|"activates"| Carcinoma["Carcinoma"]
    EOMES -->|"activates"| Als["Als"]
    EOMES -->|"activates"| Immune_Response["Immune Response"]
    EOMES -->|"activates"| PD_1["PD-1"]
    EOMES -->|"activates"| PD_L1["PD-L1"]
    B7S1["B7S1"] -->|"upregulates"| EOMES
    CD8["CD8"] -->|"activates"| EOMES
    PD_L1 -->|"activates"| EOMES
    PD_1 -->|"activates"| EOMES
    AND["AND"] -->|"activates"| EOMES
    CANCER["CANCER"] -->|"activates"| EOMES

Outgoing (30)

Target	Relation	Type	Str
Tumor	activates	disease	0.65
Cancer	activates	disease	0.65
ALS	activates	disease	0.65
Carcinoma	activates	disease	0.65
Als	activates	disease	0.65
Immune Response	activates	pathway	0.60
PD-1	activates	gene	0.60
PD-L1	activates	gene	0.60
T Cell	activates	cell_type	0.60
CANCER	activates	gene	0.60
CD8	activates	gene	0.60
AND	activates	gene	0.60
FGF18	targets	gene	0.60
FGF20	targets	gene	0.60
FZD7	targets	gene	0.60
IL10	targets	gene	0.60
JAG1	targets	gene	0.60
LEF1	targets	gene	0.60
MITF	targets	gene	0.60
MYC	targets	gene	0.60
NEUROD1	targets	gene	0.60
NOTCH2	targets	gene	0.60
NRCAM	targets	gene	0.60
PPARD	targets	gene	0.60
PTGS2	targets	gene	0.60
SNAI1	targets	gene	0.60
TERT	targets	gene	0.60
TNFRSF19	targets	gene	0.60
VEGFA	targets	gene	0.60
T Cell	expressed_in	cell_type	0.55

Incoming (16)

Source	Relation	Type	Str
B7S1	upregulates	protein	0.75
CD8	activates	gene	0.60
PD-L1	activates	gene	0.60
PD-1	activates	gene	0.60
AND	activates	gene	0.60
CANCER	activates	gene	0.60
ABCB1	targets	gene	0.60
ALDH1A1	targets	gene	0.60
ATF3	targets	gene	0.60
AXIN2	targets	gene	0.60
BAMBI	targets	gene	0.60
CCND1	targets	gene	0.60
CD44	targets	gene	0.60
CLDN1	targets	gene	0.60
CTLA4	targets	gene	0.60
DKK1	targets	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

EOMES

Understanding Entity Pages

Wiki Pages (10)

Intermediate Progenitor Cells

Olfactory Bulb Granule Cells

PSP Brainstem Degeneration

TBX3 Gene

Deep Superior Colliculus (dSC) Neurons

Tufted Cells

Paramedian Reticular Nucleus Neurons

Unipolar Brush Cells in Episodic Ataxia

Deep Cerebellar Nuclei Neurons (Expanded)